Tectorigenin: Difference between revisions
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'''Tectorigenin''' is an [[O-methylated isoflavone|''O''-methylated isoflavone]], a type of flavonoid. It ha been isolated from [[Belamcanda chinensis|leopard lily]] (''Belamcanda chinensis''),<ref>{{cite journal | doi = 10.1093/carcin/bgi092 | title = Tectorigenin and other phytochemicals extracted from leopard lily Belamcanda chinensis affect new and established targets for therapies in prostate cancer | date = 2005 | last1 = Thelen | first1 = Paul | last2 = Scharf | first2 = Jens-Gerd | last3 = Burfeind | first3 = Peter | last4 = Hemmerlein | first4 = Bernhard | last5 = Wuttke | first5 = Wolfgang | last6 = Spengler | first6 = Barbara | last7 = Christoffel | first7 = Volker | last8 = Ringert | first8 = Rolf-Hermann | last9 = Seidlová-Wuttke | first9 = Dana | journal = Carcinogenesis | volume = 26 | issue = 8 | pages = 1360–1367 | pmid = 15845653 | doi-access = free }}</ref> [[Iris unguicularis|Algerian iris]] (''Iris unguicularis'')<ref>{{cite journal | doi = 10.3987/COM-10-S(E)6 | title = New and Known Constituents from Iris unguicularis and Their Antioxidant Activity | date = 2010 | last1 = Atta-Ur-Rahman | last2 = Hareem | first2 = Sumaira | last3 = Iqbal Choudhary | first3 = M. | last4 = Sener | first4 = Bilge | last5 = Abbaskhan | first5 = Ahmed | last6 = Siddiqui | first6 = Hina | last7 = Anjum | first7 = Shazia | last8 = Orhan | first8 = Ilkay | last9 = Gurbuz | first9 = Ilhan | last10 = Ayanoglu | first10 = Filiz | journal = Heterocycles | volume = 82 | page = 813(削除) | doi-broken-date = 2024年02月11日 (削除ここまで) | doi-access = free }}</ref> and [[Pueraria thunbergiana|East Asian arrowroot]] (''Pueraria thunbergiana'').<ref>{{cite journal | doi = 10.1248/bpb.24.1117 | title = Tectorigenin, an Isoflavone of Pueraria thunbergiana BENTH., Induces Differentiation and Apoptosis in Human Promyelocytic Leukemia HL-60 Cells | date = 2001 | last1 = Lee | first1 = Kyung-Tae | last2 = Sohn | first2 = Il-Cheol | last3 = Kim | first3 = Young-Kwan | last4 = Choi | first4 = Jung-Hye | last5 = Choi | first5 = Jong-Won | last6 = Park | first6 = Hee-Juhn | last7 = Itoh | first7 = Yoshie | last8 = Miyamoto | first8 = Ken-Ichi | journal = Biological and Pharmaceutical Bulletin | volume = 24 | issue = 10 | pages = 1117–1121 | pmid = 11642314 | doi-access = free }}</ref>
'''Tectorigenin''' is an [[O-methylated isoflavone|''O''-methylated isoflavone]], a type of flavonoid. It ha been isolated from [[Belamcanda chinensis|leopard lily]] (''Belamcanda chinensis''),<ref>{{cite journal | doi = 10.1093/carcin/bgi092 | title = Tectorigenin and other phytochemicals extracted from leopard lily Belamcanda chinensis affect new and established targets for therapies in prostate cancer | date = 2005 | last1 = Thelen | first1 = Paul | last2 = Scharf | first2 = Jens-Gerd | last3 = Burfeind | first3 = Peter | last4 = Hemmerlein | first4 = Bernhard | last5 = Wuttke | first5 = Wolfgang | last6 = Spengler | first6 = Barbara | last7 = Christoffel | first7 = Volker | last8 = Ringert | first8 = Rolf-Hermann | last9 = Seidlová-Wuttke | first9 = Dana | journal = Carcinogenesis | volume = 26 | issue = 8 | pages = 1360–1367 | pmid = 15845653 | doi-access = free }}</ref> [[Iris unguicularis|Algerian iris]] (''Iris unguicularis'')<ref>{{cite journal | doi = 10.3987/COM-10-S(E)6 | title = New and Known Constituents from Iris unguicularis and Their Antioxidant Activity | date = 2010 | last1 = Atta-Ur-Rahman | last2 = Hareem | first2 = Sumaira | last3 = Iqbal Choudhary | first3 = M. | last4 = Sener | first4 = Bilge | last5 = Abbaskhan | first5 = Ahmed | last6 = Siddiqui | first6 = Hina | last7 = Anjum | first7 = Shazia | last8 = Orhan | first8 = Ilkay | last9 = Gurbuz | first9 = Ilhan | last10 = Ayanoglu | first10 = Filiz | journal = Heterocycles | volume = 82 | page = 813 | doi-access = free }}</ref> and [[Pueraria thunbergiana|East Asian arrowroot]] (''Pueraria thunbergiana'').<ref>{{cite journal | doi = 10.1248/bpb.24.1117 | title = Tectorigenin, an Isoflavone of Pueraria thunbergiana BENTH., Induces Differentiation and Apoptosis in Human Promyelocytic Leukemia HL-60 Cells | date = 2001 | last1 = Lee | first1 = Kyung-Tae | last2 = Sohn | first2 = Il-Cheol | last3 = Kim | first3 = Young-Kwan | last4 = Choi | first4 = Jung-Hye | last5 = Choi | first5 = Jong-Won | last6 = Park | first6 = Hee-Juhn | last7 = Itoh | first7 = Yoshie | last8 = Miyamoto | first8 = Ken-Ichi | journal = Biological and Pharmaceutical Bulletin | volume = 24 | issue = 10 | pages = 1117–1121 | pmid = 11642314 | doi-access = free }}</ref>
== Glycosides ==
== Glycosides ==
Latest revision as of 01:12, 18 September 2024
| Names | |
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| IUPAC name
4′,5,7-Trihydroxy-6-methoxyisoflavone
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| Systematic IUPAC name
5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one | |
| Other names
Tectorigenine
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| Identifiers | |
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3D model (JSmol)
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| ChEBI |
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| ChEMBL |
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| ChemSpider |
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| ECHA InfoCard | 100.208.621 Edit this at Wikidata |
| KEGG |
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PubChem CID
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| UNII |
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CompTox Dashboard (EPA)
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| Properties | |
| C16H12O6 | |
| Molar mass | 300.266 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Tectorigenin is an O-methylated isoflavone, a type of flavonoid. It ha been isolated from leopard lily (Belamcanda chinensis),[1] Algerian iris (Iris unguicularis)[2] and East Asian arrowroot (Pueraria thunbergiana).[3]
Glycosides
[edit ]Tectoridin is the 7-glucoside of tectorigenin.
See also
[edit ]- ψ-Tectorigenin, an isomeric flavonoid
References
[edit ]- ^ Thelen, Paul; Scharf, Jens-Gerd; Burfeind, Peter; Hemmerlein, Bernhard; Wuttke, Wolfgang; Spengler, Barbara; Christoffel, Volker; Ringert, Rolf-Hermann; Seidlová-Wuttke, Dana (2005). "Tectorigenin and other phytochemicals extracted from leopard lily Belamcanda chinensis affect new and established targets for therapies in prostate cancer". Carcinogenesis. 26 (8): 1360–1367. doi:10.1093/carcin/bgi092 . PMID 15845653.
- ^ Atta-Ur-Rahman; Hareem, Sumaira; Iqbal Choudhary, M.; Sener, Bilge; Abbaskhan, Ahmed; Siddiqui, Hina; Anjum, Shazia; Orhan, Ilkay; Gurbuz, Ilhan; Ayanoglu, Filiz (2010). "New and Known Constituents from Iris unguicularis and Their Antioxidant Activity". Heterocycles. 82: 813. doi:10.3987/COM-10-S(E)6 .
- ^ Lee, Kyung-Tae; Sohn, Il-Cheol; Kim, Young-Kwan; Choi, Jung-Hye; Choi, Jong-Won; Park, Hee-Juhn; Itoh, Yoshie; Miyamoto, Ken-Ichi (2001). "Tectorigenin, an Isoflavone of Pueraria thunbergiana BENTH., Induces Differentiation and Apoptosis in Human Promyelocytic Leukemia HL-60 Cells". Biological and Pharmaceutical Bulletin. 24 (10): 1117–1121. doi:10.1248/bpb.24.1117 . PMID 11642314.
