One useful feature of the sqlite3 module is the builtin sqlite3.Row class designed to be used as a row factory.
Rows wrapped with this class can be accessed both by index (like tuples) and case-insensitively by name:
import sqlite3
con = sqlite3.connect("mydb")
con.row_factory = sqlite3.Row
cur = con.cursor()
cur.execute("select name_last, age from people")
for row in cur:
assert row[0] == row["name_last"]
assert row["name_last"] == row["nAmE_lAsT"]
assert row[1] == row["age"]
assert row[1] == row["AgE"]