内容説明
With the enormous development of human and mouse genomics and the availability of a variety of transgenic techniques, the mouse has become the most widely used animal for basic studies of brain development and as a model for human developmental disorders. The topics are addressed using a diversity of techniques, from genetic, biochemical and cell biological to morphological and functional. The conceptual approaches also provide a framework for studies of other problems and point the way towards future research.
目次
Introduction * Mapping Genes that Modulate Mouse Brain Development * Genetic Interactions During Hindbrain Segmentation in the Mouse Embryo * Neurogenetic Compartments of the Mouse Diencephalon and Some Characteristic Gene Expression Patterns * Neuronogenesis and the Early Events of Neocortical Histogenesis * Programmed Cell Death in Mouse Brain Development * Neurotrophic Factors: Versatile Signals for Cell-Cell Communication in the Nervous System * Growth Factors' Influences on the Production and Migration of Cortical Neurons * Signalling From Tyrosine Kinases in the Developing Neurons and Glia of the Mammalian Brain * The Role of the p35/cdk5 Kinase in Cortical Development * The Reelin Signalling Pathway and Mouse Brain Development * The Subpial Granular Layer in the Developing Cerebral Cortex of Rodents * Development of Thalamocortical Projections in Normal and Mutant Mice.
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