Heart failure : pathophysiology, molecular biology and clinical management

Bibliographic Information

Heart failure : pathophysiology, molecular biology and clinical management

Arnold M. Katz

Lippincott Williams & Wilkins, 1999

Available at  / 13 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

Written by a distinguished authority in cardiac physiology, this volume explains and integrates the many mechanisms responsible for heart failure. The chapters examine impaired pump function, neurohumoral responses to reduced cardiac output, and contraction and relaxation abnormalities. The author explains why physiologic processes and pharmacologic therapies that are adaptive or helpful over the short term often have deleterious long-term consequences. The coverage includes detailed analyses of underlying molecular mechanisms, clinical manifestations, and therapy.

Table of Contents

  • Preface Overview, Definition, Historical Aspects Organ Physiology:The Failing Heart as a Weakened Pump Cell Biochemistry:Abnormal Excitation-Contraction Coupling,Contraction, and Relaxation
  • Arrhythmias
  • Energy Starvation The Hemodynamic Defense Reaction Neurohumoral Response:The Inflammatory Response The Hypertrophic Response:Programmed Cell Death Signal Transduction Within Cells of the Failing Heart Maladaptive Hypertrophy and the Cardiomyopathy of Overload:Familial Cardiomyopathies Therapeutic Strategies for Managing Heart Failure Care of the Heart Failure Patient Inde

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