Neurotransmitter receptors

Bibliographic Information

Neurotransmitter receptors

editor Ferdinand Hucho

(New comprehensive biochemistry / general editors, A. Neuberger, L.L.M. van Deenen, v. 24)

Elsevier, 1993

Available at  / 32 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

This comprehensive compilation provides a information on receptor sequences produced by recombinant DNA techniques used in combination with classical biochemistry. To minimize redundancies in this wealth of information, only a few receptors (some of which are typical for a whole group of similar receptors, others which are presently of special interest) are dealt with in a full-size chapter. Others are represented in the "TIPS Receptor Nomenclature Supplement" which is included as a special feature in this book, making this volume more useful as a receptor handbook.

Table of Contents

  • Part 1 General Topics: Transmitter receptors - general principles and nomenclature, F. Hucho
  • Historical aspects and definition. "TiPS Receptor Nomenclature Supplement 1993". Ligand binding studies - theory and experimental techniques, H. Otto
  • The experimental scenario
  • Experimental strategies
  • Experimental techniques
  • Receptor regulation, F. Nantel, M. Bouvier
  • Receptor regulation. Part 2 "Prototype Receptors": The nicotinic acetylcholine receptor, F. Hucho
  • Function and occurrence
  • Pharmacology and toxicology
  • Biochemistry
  • The Beta-adrenergic receptor, M. Lohse, E.J.M. Helmreich
  • Pharmacological characterization
  • Function and structure
  • Regulation of Beta-adrenoceptor function
  • Clinical aspects
  • Outlook. Part 3 Receptors for "Classic" neurotransmitters: GABAA and glycine receptors, A. Stephenson
  • GABAA and glycine receptor molecular pharmacology
  • GABAA and glycine receptors biochemistry and molecular biology
  • Oligometric receptor structures and their distribution
  • Functional properties of cloned GABAA and glycine receptors
  • GABAA and glycine receptors in disease states
  • Muscarinic acetylcholine receptors, J. Jaerv, A. Rinken
  • Phenomena used for receptor assay
  • Compounds interacting with the receptor
  • Pharmacological and molecular subtypes of muscarinic receptor
  • Receptor molecule
  • Ligand-receptor interactions
  • Mechanisms of signal transduction
  • Two-site receptor model
  • Receptors for 5-hydroxytryptamine, D.H. Bobker, J.T. Williams
  • History
  • Nomenclature
  • Biochemistry of 5-HT synthesis, storage and neurotransmission
  • Anatomy of central serotonin
  • 5-HT1A receptor
  • 5-HT1B and 5-HT1D receptors
  • 5-HT1C receptor
  • 5-HT2 receptors
  • 5-HT3 receptor
  • 5-HT receptors that stimulate adenylate cyclase
  • Molecular biology
  • Dopamine receptors, P.G. Strange
  • Functions and distribution of dopamine receptors
  • Dopamine receptor subtypes - definitions and overall properties
  • Biochemical characterization of dopamine receptors
  • Glutamate receptors, G.E. Fagg, A.C. Foster
  • Function and occurrence
  • Pharmacology and toxicology
  • Molecular biology
  • Miscellaneous effects
  • Opioid receptors, E.A. Barnard, J. Simon
  • Multiple opioid receptors and their ligands
  • Subtypes of opioid receptor types
  • Cellular mechanisms of opioid actions
  • The states of opioid receptors in the membrane
  • Solubilization and purification of opioid receptors
  • Molecular biology of opioid receptors
  • Guanylyl cyclases as effectors of hormone and neurotransmitter receptor, D. Koesling, E. Boehme, G. Schultz. (Part contents).

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