α-adrenoceptors : signal transduction, ionic channels, and effector organs : proceedings of the 9/10th α-adrenoceptors conference, Tokyo, August 30-31, 1991

書誌事項

α-adrenoceptors : signal transduction, ionic channels, and effector organs : proceedings of the 9/10th α-adrenoceptors conference, Tokyo, August 30-31, 1991

editors, Motohatsu Fujiwara, Tsuneaki Sugimoto, Kyuya Kogure

(Current clinical practice series, 63)

Excerpta Medica, 1992

この図書・雑誌をさがす

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Along with others in the series, this book presents and discusses the results of research and exchange information on alpha-adrenoceptors from the viewpoint of both basic and clinical medicine. This volume focuses on the latest research on the structure, function and regulation of alpha-adrenoceptors, receptor-coupled ionic channels, and signal transduction and effectors of alpha-adrenoceptors. The book should be of interest to pharmacologists, molecular biologists and neurologists, and hopes to stimulate young researchers, in particular, to take up both clinical and basic research in this area.

目次

  • Part 1 Signal transduction: phosphorylation by nucleotide diphosphate kinase of GDP-bound alpha-subunits of G protein, M. Ui et al
  • role of phospholipid breakdown in signal transduction, J.H. Exton et al
  • protein kinase C in transmembrane signalling cascade, Y. Asaoka et al
  • stimulus-transcription coupling in the nervous system - from proto-oncogenes to transgenes, J.I. Morgan et al
  • structure and function of the inositol 1,4,5-trisphosphate receptor, K. Mikosiba et al
  • myocardial alpha1-adrenoceptor-mediated signal tranduction process - receptor subtypes and phosphoinositide hydrolysis, M. Endoh et al
  • mechanism of alpha-adrenoceptor-mediated contraction in vascular smooth muscle, H. Karaki. Part 2 Effectors: possible mechanisms of the positive inotropic effect of alpha-adrenergic receptor stimulation in the heart, H. Scholz et al
  • alterations in alpha-adrenergic receptors in response to myocardial ischemia and their role in arrhythmogenesis, T. Kurz et al
  • neurotransmitter receptors after ischemic brain damage, H. Onodera. Part 3 Receptor-coupled ionic channels: interaction between the voltage-operated calcium channel and receptor-operated nonselective cation channel in vascular smooth muscle, M. Oike et al
  • receptor-dependent modulation of the G protein-gated muscarinic K+ channel by arachidonic acid metabolites, Y. Kurachi. Part 4 Structure and function: desensitization of alpha-adrenergic receptor-mediated smooth muscle contraction, B.B. Hoffman and Z.-W. Hu
  • molecular characterization of the family of alpha-adrenergic receptors, M.G. Caron
  • a pharmacological perspective of alpha1-adrenoceptors - subclassification and functional aspects, I. Muramatsu. Part 5 Short communications: role of beta-adrenergic receptors in human benign prostatic hyperplasia, T. Tsujii et al
  • different roles of central alpha- and beta-adrenoceptors in the regulation of yawning responses in rats, H. Kimura et al
  • alpha-adrenoceptor-mediated inhibition of endogenous norepinephrine release from vascularly perfused rat stomach in vitro, K. Yokotani et al
  • alpha1-adrenergic-mediated increase in cytosolic Ca2+ and cyclic AMP in isolated rat hepatocytes, T. Nomura et al
  • purification and reconstitution of opioid receptors, T. Fujioka et al
  • renal adenylate cyclase-cyclic AMP system in spontaneously hypertensive rats - effects of parathyroid hormone, prostaglandin and alpha2-adrenergic receptor stimulation, S. Umemura et al
  • interference of a selective mesenteric vasodilator peptide, urotensin I, with adrenergic pressor responses, H. Itoh et al
  • altered cardiovascular and renal responses to central alpha2-adrenoceptor agonist (clonidine) in noninsulin-dependent diabetes mellitus, K. Tanaka et al
  • effect of an angiotensin-converting enzyme inhibitor (enalapril) on first-dose hypotension by an alpha1-adrenoceptor blocker (bunazosin), N. Yamada et al. (part contents)

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