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Marshal is the wrong place for this sort of thing (the code object is
where it should be done).
I botched the analysis. The case is common, but only for the empty
tuple which I forgot to ignore. (None,) was a common case when I
measured it. We should measure the actual memory savings before
anything is implemented.
To answer your question, the case were this happens is:
 def foo(self): return self.self