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A frequent newbie mistake is to call shell commands from inside the interactive interpreter. Most common is to call Python itself.
Here is an example where a Python instructor was allegedly unable to diagnose the issue for their students:
https://windowsquestions.com/2021/10/09/syntaxerror-invalid-syntax-perhaps-you-forgot-a-comma/
I think it would be a nice feature if the compiler recognised obvious cases of "user tried to call Python from the Python prompt", and suggested a fix. If the statement matches the regex r"python\s+" the error message might say "it looks like you are trying to run a shell command at the Python prompt" rather than suggest a missing comma.