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To get one GIL per interpreter (bpo-40512), remaining _PyRuntimeState.ceval members should be moved to PyInterpreterState.ceval. The work started in bpo-39984 with ceval "pending calls" and ceval "eval breaker".
There are 4 remaining fields:
struct _ceval_runtime_state {
 int recursion_limit;
 /* Request for dropping the GIL */
 _Py_atomic_int gil_drop_request;
 /* Request for checking signals. */
 _Py_atomic_int signals_pending;
 struct _gil_runtime_state gil;
};
The most complex part will be to move the "gil" member: bpo-40512 lists all sub-tasks which must be completed before being able to have one GIL per interpreter without crashing.