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at least on my Windows, the following code:
import sys
sys.modules = []
- when run interactively, causes weird behavior, e.g. exit() doesn't exit the
 interpreter, and print() doesn't print.
 then, pressing Ctrl+C causes 'Assertion failed: !PyErr_Occurred(), file ..\Objects\call.c, line 803'
- when run as a script, causes PyImport_Cleanup() to raise a negative ref count
 Fatal Python error.
 (this is because PyImport_Cleanup() (in Python/import.c) assumes that
 PyImport_GetModuleDict() returned a dict.)
IIUC, this bug was introduced in https://github.com/python/cpython/pull/1638
(which resolved #28411).