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i consider uuids as low level data types, not as fancy containers, similar to how i view datetime objects. given the native support in e.g. postgresql and many other systems, it's common to deal with uuids.
of course you can convert to/from strings or numbers, but that is cumbersome in many cases. for comparison, one would typically not convert unicode text from/into utf-8 encoded byte strings either, even though the latter will save memory in many cases.
from experience: converting can lead to nasty bugs, e.g. because you forgot about a conversion, and then a uuid string does not compare equal to a uuid.UUID instance, leaving you puzzled.