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I think it is worth to add special helper in test.support for using as a context manager:
 with helper():
 os.mkfifo(filename)
Then you could change its implementation without changing the testing code. For example:
 @contextmanager
 def helper():
 try:
 yield
 except PermissionError as e:
 raise unittest.SkipTest(str(e))
or
 @contextmanager
 def helper():
 if android_not_root:
 raise unittest.SkipTest("operation not allowed, non root user")
 yield