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inspect.signature fails on some functions which use Argument Clinic. For example after applying issue20133 or issue20151 it fails for audioop.ratecv and binascii.a2b_qp.
>>> inspect.signature(audioop.ratecv)
Traceback (most recent call last):
 File "<stdin>", line 1, in <module>
 File "/home/serhiy/py/cpython/Lib/inspect.py", line 1468, in signature
 return Signature.from_builtin(obj)
 File "/home/serhiy/py/cpython/Lib/inspect.py", line 1989, in from_builtin
 p(name, default)
 File "/home/serhiy/py/cpython/Lib/inspect.py", line 1982, in p
 default = default.n
AttributeError: type object '_empty' has no attribute 'n'