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This might be a duplicate of issue17053, but the patch provided there doesn't resolve the issue, at least as far as I know it. Here is an example, from David Beazley's talk at PyCon 2013:
from inspect import Parameter, Signature
def make_signature(names):
 return Signature(
 Parameter(name, Parameter.POSITIONAL_OR_KEYWORD) for name in names)
class Structure:
 __signature__ = make_signature([])
 def __init__(self, *args, **kwargs):
 bound = self.__signature__.bind(*args, **kwargs)
 for name, val in bound.arguments.items():
 setattr(self, name, val)
class Stock(Structure):
 __signature__ = make_signature(['name', 'shares', 'price'])
pyth = Stock('PYTH', 100, 50)
help(pyth.__init__)
Which produces:
__init__(self, *args, **kwargs) method of __main__.Stock instance
Instead of:
__init__(self, name, shares, price) method of __main__.Stock instance