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There seems to be a bootstrap issue here. Building with ./configure --with-pydebug --prefix=... on OS X in a clean source directory (hg purge --all), 'make' makes it to building the static libpython .a but then dies on the sysconfig generate-posix-vars step:
ar rc libpython3.4dm.a Modules/_threadmodule.o Modules/signalmodule.o Modules/posixmodule.o Modules/errnomodule.o Modules/pwdmodule.o Modules/_sre.o Modules/_codecsmodule.o Modules/_weakref.o Modules/_functoolsmodule.o Modules/operator.o Modules/_collectionsmodule.o Modules/itertoolsmodule.o Modules/_localemodule.o Modules/_iomodule.o Modules/iobase.o Modules/fileio.o Modules/bytesio.o Modules/bufferedio.o Modules/textio.o Modules/stringio.o Modules/zipimport.o Modules/faulthandler.o Modules/symtablemodule.o Modules/xxsubtype.o
/usr/bin/ranlib: file: libpython3.4dm.a(dynamic_annotations.o) has no symbols
/usr/bin/ranlib: file: libpython3.4dm.a(pymath.o) has no symbols
ranlib libpython3.4dm.a
ranlib: file: libpython3.4dm.a(dynamic_annotations.o) has no symbols
ranlib: file: libpython3.4dm.a(pymath.o) has no symbols
/usr/bin/clang -framework CoreFoundation -o python Modules/python.o libpython3.4dm.a -ldl -framework CoreFoundation 
./python -E -S -m sysconfig --generate-posix-vars
Could not find platform dependent libraries <exec_prefix>
Consider setting $PYTHONHOME to <prefix>[:<exec_prefix>]
Traceback (most recent call last):
 File "/py/dev/default/b10.7_t10.7_x4.3_cclang_d/unix/source/Lib/runpy.py", line 160, in _run_module_as_main
 "__main__", fname, loader, pkg_name)
 File "/py/dev/default/b10.7_t10.7_x4.3_cclang_d/unix/source/Lib/runpy.py", line 73, in _run_code
 exec(code, run_globals)
 File "/py/dev/default/b10.7_t10.7_x4.3_cclang_d/unix/source/Lib/sysconfig.py", line 683, in <module>
 _main()
 File "/py/dev/default/b10.7_t10.7_x4.3_cclang_d/unix/source/Lib/sysconfig.py", line 671, in _main
 _generate_posix_vars()
 File "/py/dev/default/b10.7_t10.7_x4.3_cclang_d/unix/source/Lib/sysconfig.py", line 374, in _generate_posix_vars
 pybuilddir = 'build/lib.%s-%s' % (get_platform(), sys.version[:3])
 File "/py/dev/default/b10.7_t10.7_x4.3_cclang_d/unix/source/Lib/sysconfig.py", line 651, in get_platform
 get_config_vars(),
 File "/py/dev/default/b10.7_t10.7_x4.3_cclang_d/unix/source/Lib/sysconfig.py", line 520, in get_config_vars
 _init_posix(_CONFIG_VARS)
 File "/py/dev/default/b10.7_t10.7_x4.3_cclang_d/unix/source/Lib/sysconfig.py", line 393, in _init_posix
 from _sysconfigdata import build_time_vars
ImportError: No module named '_sysconfigdata'