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pkgutil is used by runpy to run Python modules that are loaded via the -m command line switch.
Unfortunately, this doesn't work for frozen modules, since pkgutil doesn't know how to load their code object (this can be had via imp.get_code_object() for frozen modules).
We found the problem while working on eGenix PyRun (see http://www.egenix.com/products/python/PyRun/) which uses frozen modules extensively. We currently only target Python 2.x, so will have work around the problem with a patch, but Python 3.x still has the same problem.