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I tried to install 2.7.5 on my OpenSuse 12.2 (latest patches)
ajung@blackmoon2:~/sandboxes/mib.portal> cat /etc/issue
Welcome to openSUSE 12.2 "Mantis" - Kernel \r (\l).
Compilation went fine (no visible errors).
Starting the interpreter gives me:
ajung@blackmoon2:~/sandboxes/mib.portal> /opt/python-2.7.5/bin/python 
Could not find platform dependent libraries <exec_prefix>
Consider setting $PYTHONHOME to <prefix>[:<exec_prefix>]
Python 2.7.5 (default, May 29 2013, 08:19:10) 
[GCC 4.7.1 20120723 [gcc-4_7-branch revision 189773]] on linux2
Type "help", "copyright", "credits" or "license" for more information.
>>> 
Trying to bootstrap a Pyramid project using zc.buildout gives me:
ajung@blackmoon2:~/sandboxes/mib.portal> /opt/python-2.7.5/bin/python bootstrap.py 
Could not find platform dependent libraries <exec_prefix>
Consider setting $PYTHONHOME to <prefix>[:<exec_prefix>]
Traceback (most recent call last):
 File "bootstrap.py", line 21, in <module>
 import os, shutil, sys, tempfile, urllib, urllib2, subprocess
 File "/opt/python-2.7.5/lib/python2.7/shutil.py", line 12, in <module>
 import collections
 File "/opt/python-2.7.5/lib/python2.7/collections.py", line 8, in <module>
 from _collections import deque, defaultdict
ImportError: No module named _collections

Without more information, it is difficult to guess what is going wrong. Please provide exactly what ./configure options you used to build Python and any "make install" options. When you start Python, what values do "sys.prefix", "sys.exec_prefix", and "sys.path" have? Does "python -E" give any different results?

I guess you are on a 64bit os an the issue is a variant of issue1294959. Some of the components (scripts) are installed in the $PREFIX/lib folder and some are (libs) installed in the $PREFIX/lib64 folder. a workaround which worked for me (on OpenSuse 12.3 which faced the same issue) is specifying a lib directory on configure like this:
> ./configure --prefix=/opt/Python275 --libdir=/opt/Python275/lib
All components (scripts & libs) are in the $PREFIX/lib folder then.