MSstatsResponse

This is the released version of MSstatsResponse; for the devel version, see MSstatsResponse.

Statistical Methods for Chemoproteomics Dose-Response Analysis

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DOI: 10.18129/B9.bioc.MSstatsResponse

Bioconductor version: Release (3.22)

Tools for detecting drug-protein interactions and estimating IC50 values from chemoproteomics data. Implements semi-parametric isotonic regression, bootstrapping, and curve fitting to evaluate compound effects on protein abundance.

Author: Sarah Szvetecz [aut, cre], Devon Kohler [aut], Olga Vitek [aut]

Maintainer: Sarah Szvetecz <szvetecz.s at northeastern.edu>

Citation (from within R, enter citation("MSstatsResponse")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
 install.packages("BiocManager")
BiocManager::install("MSstatsResponse")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MSstatsResponse")

MSstatsResponse User Guide HTML R Script

Reference Manual PDF

NEWS Text

Need some help? Ask on the Bioconductor Support site!

Details

biocViews MassSpectrometry, Proteomics, Regression, Software, StatisticalMethod

Version 1.0.0

In Bioconductor since BioC 3.22 (R-4.5) (< 6 months)

License Artistic-2.0

Depends R (>= 4.5.0)

Imports BiocParallel, ggplot2, dplyr, stats, parallel, data.table

System Requirements

URL https://github.com/Vitek-Lab/MSstatsResponse

Bug Reports https://github.com/Vitek-Lab/MSstatsResponse/issues

Suggests MSstats, MSstatsTMT, tidyverse, boot, purrr, gridExtra, knitr, rmarkdown, BiocStyle, testthat

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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MSstatsResponse_1.0.0.tar.gz

Windows Binary (x86_64)

macOS Binary (x86_64) MSstatsResponse_1.0.0.tgz

macOS Binary (arm64) MSstatsResponse_1.0.0.tgz

Source Repository git clone https://git.bioconductor.org/packages/MSstatsResponse

Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/MSstatsResponse

Bioc Package Browser https://code.bioconductor.org/browse/MSstatsResponse/

Package Short Url https://bioconductor.org/packages/MSstatsResponse/

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