methyLImp2

This is the development version of methyLImp2; for the stable release version, see methyLImp2.

Missing value estimation of DNA methylation data

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DOI: 10.18129/B9.bioc.methyLImp2

Bioconductor version: Development (3.23)

This package allows to estimate missing values in DNA methylation data. methyLImp method is based on linear regression since methylation levels show a high degree of inter-sample correlation. Implementation is parallelised over chromosomes since probes on different chromosomes are usually independent. Mini-batch approach to reduce the runtime in case of large number of samples is available.

Author: Pietro Di Lena [aut] ORCID iD ORCID: 0000-0002-1838-8918 , Anna Plaksienko [aut, cre] ORCID iD ORCID: 0000-0001-9607-057X , Claudia Angelini [aut] ORCID iD ORCID: 0000-0001-8350-8464 , Christine Nardini [aut] ORCID iD ORCID: 0000-0001-7601-321X

Maintainer: Anna Plaksienko <anna at plaxienko.com>

Citation (from within R, enter citation("methyLImp2")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
 install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("methyLImp2")

For older versions of R, please refer to the appropriate Bioconductor release.