genomicInstability

This is the development version of genomicInstability; for the stable release version, see genomicInstability.

Genomic Instability estimation for scRNA-Seq

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DOI: 10.18129/B9.bioc.genomicInstability

Bioconductor version: Development (3.23)

This package contain functions to run genomic instability analysis (GIA) from scRNA-Seq data. GIA estimates the association between gene expression and genomic location of the coding genes. It uses the aREA algorithm to quantify the enrichment of sets of contiguous genes (loci-blocks) on the gene expression profiles and estimates the Genomic Instability Score (GIS) for each analyzed cell.

Author: Mariano Alvarez [aut, cre], Pasquale Laise [aut], DarwinHealth [cph]

Maintainer: Mariano Alvarez <reef103 at gmail.com>

Citation (from within R, enter citation("genomicInstability")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
 install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("genomicInstability")

For older versions of R, please refer to the appropriate Bioconductor release.