TOAST

This is the development version of TOAST; for the stable release version, see TOAST.

Tools for the analysis of heterogeneous tissues

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DOI: 10.18129/B9.bioc.TOAST

Bioconductor version: Development (3.23)

This package is devoted to analyzing high-throughput data (e.g. gene expression microarray, DNA methylation microarray, RNA-seq) from complex tissues. Current functionalities include 1. detect cell-type specific or cross-cell type differential signals 2. tree-based differential analysis 3. improve variable selection in reference-free deconvolution 4. partial reference-free deconvolution with prior knowledge.

Author: Ziyi Li and Weiwei Zhang and Luxiao Chen and Hao Wu

Maintainer: Ziyi Li <zli16 at mdanderson.org>

Citation (from within R, enter citation("TOAST")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
 install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("TOAST")

For older versions of R, please refer to the appropriate Bioconductor release.