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Melissa
This is the development version of Melissa; for the stable release version, see Melissa.
Bayesian clustering and imputationa of single cell methylomes
Bioconductor version: Development (3.23)
Melissa is a Baysian probabilistic model for jointly clustering and imputing single cell methylomes. This is done by taking into account local correlations via a Generalised Linear Model approach and global similarities using a mixture modelling approach.
Author: C. A. Kapourani [aut, cre]
Maintainer: C. A. Kapourani <kapouranis.andreas at gmail.com>
Citation (from within R, enter
citation("Melissa")):
Installation
To install this package, start R (version "4.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("Melissa")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
Reference Manual
PDF
Details
biocViews
Bayesian, Clustering, Coverage, DNAMethylation, Epigenetics, FeatureExtraction, GeneExpression, GeneRegulation, Genetics, ImmunoOncology, KEGG, RNASeq, Regression, Sequencing, SingleCell, Software
Version
1.27.0
In Bioconductor since
BioC 3.9 (R-3.6) (6.5 years)
License
GPL-3 | file LICENSE
Depends
R (>= 3.5.0), BPRMeth, GenomicRanges
Imports
data.table, parallel, ROCR, matrixcalc, mclust, ggplot2, doParallel, foreach, MCMCpack, cowplot, magrittr, mvtnorm, truncnorm, assertthat, BiocStyle, stats, utils
System Requirements
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Follow Installation instructions to use this package in your R session.
Windows Binary (x86_64)
Source Repository
git clone https://git.bioconductor.org/packages/Melissa
Source Repository (Developer Access)
git clone git@git.bioconductor.org:packages/Melissa
Package Short Url
https://bioconductor.org/packages/Melissa/
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