COMPASS

This is the development version of COMPASS; for the stable release version, see COMPASS.

Combinatorial Polyfunctionality Analysis of Single Cells

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DOI: 10.18129/B9.bioc.COMPASS

Bioconductor version: Development (3.23)

COMPASS is a statistical framework that enables unbiased analysis of antigen-specific T-cell subsets. COMPASS uses a Bayesian hierarchical framework to model all observed cell-subsets and select the most likely to be antigen-specific while regularizing the small cell counts that often arise in multi-parameter space. The model provides a posterior probability of specificity for each cell subset and each sample, which can be used to profile a subject's immune response to external stimuli such as infection or vaccination.

Author: Lynn Lin, Kevin Ushey, Greg Finak, Ravio Kolde (pheatmap)

Maintainer: Greg Finak <gfinak at fhcrc.org>

Citation (from within R, enter citation("COMPASS")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
 install.packages("BiocManager")
# The following initializes usage of Bioc devel
BiocManager::install(version='devel')
BiocManager::install("COMPASS")

For older versions of R, please refer to the appropriate Bioconductor release.