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LineagePulse
This package is for version 3.9 of Bioconductor. This package has been removed from Bioconductor. For the last stable, up-to-date release version, see LineagePulse.
Differential expression analysis and model fitting for single-cell RNA-seq data
Bioconductor version: 3.9
LineagePulse is a differential expression and expression model fitting package tailored to single-cell RNA-seq data (scRNA-seq). LineagePulse accounts for batch effects, drop-out and variable sequencing depth. One can use LineagePulse to perform longitudinal differential expression analysis across pseudotime as a continuous coordinate or between discrete groups of cells (e.g. pre-defined clusters or experimental conditions). Expression model fits can be directly extracted from LineagePulse.
Author: David S Fischer [aut, cre], Fabian Theis [ctb], Nir Yosef [ctb]
Maintainer: David S Fischer <david.fischer at helmholtz-muenchen.de>
citation("LineagePulse")):
Installation
To install this package, start R (version "3.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("LineagePulse")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("LineagePulse")
Details
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Package Archives
Follow Installation instructions to use this package in your R session.