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Uniquorn
This package is for version 3.21 of Bioconductor; for the stable, up-to-date release version, see Uniquorn.
Identification of cancer cell lines based on their weighted mutational/ variational fingerprint
Bioconductor version: 3.21
'Uniquorn' enables users to identify cancer cell lines. Cancer cell line misidentification and cross-contamination reprents a significant challenge for cancer researchers. The identification is vital and in the frame of this package based on the locations/ loci of somatic and germline mutations/ variations. The input format is vcf/ vcf.gz and the files have to contain a single cancer cell line sample (i.e. a single member/genotype/gt column in the vcf file).
Author: Raik Otto
Maintainer: 'Raik Otto' <raik.otto at hu-berlin.de>
citation("Uniquorn")):
Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("Uniquorn")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("Uniquorn")
Details
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Follow Installation instructions to use this package in your R session.