Summix
This package is for version 3.21 of Bioconductor; for the stable, up-to-date release version, see Summix.
Summix2: A suite of methods to estimate, adjust, and leverage substructure in genetic summary data
Bioconductor version: 3.21
This package contains the Summix2 method for estimating and adjusting for substructure in genetic summary allele frequency data. The function summix() estimates reference group proportions using a mixture model. The adjAF() function produces adjusted allele frequencies for an observed group with reference group proportions matching a target individual or sample. The summix_local() function estimates local ancestry mixture proportions and performs selection scans in genetic summary data.
Author: Audrey Hendricks [cre], Price Adelle [aut], Stoneman Haley [aut]
Maintainer: Audrey Hendricks <audrey.hendricks at cuanschutz.edu>
citation("Summix")):
Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("Summix")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("Summix")
Details
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Follow Installation instructions to use this package in your R session.