awst
This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see awst.
Asymmetric Within-Sample Transformation
Bioconductor version: 3.16
We propose an Asymmetric Within-Sample Transformation (AWST) to regularize RNA-seq read counts and reduce the effect of noise on the classification of samples. AWST comprises two main steps: standardization and smoothing. These steps transform gene expression data to reduce the noise of the lowly expressed features, which suffer from background effects and low signal-to-noise ratio, and the influence of the highly expressed features, which may be the result of amplification bias and other experimental artifacts.
Author: Davide Risso [aut, cre, cph] , Stefano Pagnotta [aut, cph]
Maintainer: Davide Risso <risso.davide at gmail.com>
citation("awst")):
Installation
To install this package, start R (version "4.2") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("awst")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("awst")
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Follow Installation instructions to use this package in your R session.