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I have some troubleshooting steps here: Have I bricked my Arduino Uno? Problems with uploading to board

Whilst specifically written for the Uno, a lot of it applies to the Mega. Depending on what you did, the entire board may not have failed.

Many of the components are SMD (surface mounted devices) and may be difficult to replace, unless you have specialized equipment.

If you "zapped" every chip by applying a negative voltage (say) then it might not be worth it.