ZIRC is supported by an NIH grant from the Office of Research Infrastructure Programs
(ORIP) in collaboration with the Eunice Kennedy Shriver National Institute of Child Health and Human Development
(NICHD).
Research Emphasis/Objectives
-
The Zebrafish International Resource Center is housed on the
University of Oregon
campus in
Eugene.
Its mission is to provide
a central repository for wild-type and mutant strains of zebrafish
(Danio rerio) and for materials and information about zebrafish
research. Materials and zebrafish strains are distributed to the research
community. Pathology services are provided for diseased fish. Standards and
procedures for maintaining healthy strains of zebrafish are being developed
and a manual,
Diseases of Zebrafish in Research Facilities, for prevention,
diagnosis, and treatment of diseases affecting zebrafish, is available.
Resources Provided
-
Animals
-
Healthy stocks of zebrafish and frozen sperm are maintained and distributed to the research community. Strains of wild-type fish and lines carrying mutations and transgenes are accepted from the research community, maintained, and distributed upon request. Researchers are welcome to visit the Resource Center to screen the collection for mutations of interest or to learn procedures.
-
Animal Health
-
Advice about zebrafish health is provided. Diseased fish and tissue samples may be sent to the Resource Center for
pathology analysis. The Resource Center maintains
Diseases of Zebrafish in Research Facilities that describes
diseases of importance to laboratory zebrafish culture.
-
Biological Materials
-
Antibodies, gene probes, and other markers to analyze wild-type and mutant stocks are received, stored, and distributed.
Prices
-
Nominal prices are charged for some of these
materials and services.
Informatics
-
ZIRC and ZFIN
are sister
organizations. ZIRC pages provide information about available resources and
services, and they are extensively cross-linked to ZFIN.
ZFIN is an on-line database of information about zebrafish
genetics, genomics, and development. Information about the resources and
services provided by the Resource Center are also available on the ZFIN site,
as well as a listing of zebrafish researchers, laboratories, and publications.
ZFIN integrates information about the genetic map being generated by the
zebrafish genome initiative and provides links to related information about
genes in other species-specific databases. Researchers can use ZFIN to
register and submit to the nomenclature committee new names for mutant alleles
and for genes identified by molecular cloning.
Acknowledging Materials and Services
-
Please acknowledge the Zebrafish International Resource Center in all publications resulting from the materials and/or services we are providing to you. Thank you.
More Detailed Information