Further, the expression of the PPAR[gamma] coactivator 1 [alpha], which is recruited by PPAR[gamma] to
transactivate its target genes, was shown to be specifically up-regulated by BPS in the 3T3-L1 cell line (Helies-Toussaint et al.
We expected the increase in the level of p53 protein of these resistant sublines by cisplatin induced DNA- damage Althoughp53 is known to
transactivate bax, it suppresses bcl- 2 expression and the magnitude of p53 suppression of bcl- 2 expression may be tissue-specific .
LncRNAs
transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements.
So far, 7-methoxycoumarin failed to
transactivate ER[beta] such as F.
Likewise, FXR can directly
transactivate the ABCC2, ABCB4, and SLCO1B3 genes [36, 37].
Maquat, "lncRNAs
transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements," Nature, vol.
As a transcription factor, can KLF7 directly
transactivate IL-6?
Also consistent with the ability of the [AT.sub.1] receptor to promote cancer cell growth, the [AT.sub.1] receptor can
transactivate the EGF receptor, a known oncogenic stimulus [16].
PPAR RXR heterodimers
transactivate genes by binding specific sequences in the promotor regions of these genes.
Remarkably, current studies have focused on the impact of p53 to
transactivate genes involved in aerobic metabolism.
They can
transactivate some promoters but are completely inactive on others.
Leptin interacts with insulin-like growth factor-1 in triple-negative breast cancer cells to
transactivate the epidermal growth factor receptor and so promote tumor cell proliferation, migration, and invasion [43].