spectrin

spec·trin

(spĕk′trĭn)

A fibrous protein that links with actin filaments and is the major component of the sturdy cytoskeleton that underlies the plasma membrane of red blood cells.

[spect(e)r (so called because a red blood cell without hemoglobin is called a ghost) + -in.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

spectrin

(ˈspɛktrɪn)

(Biochemistry) any one of a class of fibrous proteins found in the membranes of red blood cells, the brain, the intestine, etc

[C20: from spectr(e) + -in, referring to the ghosts (isolated cell membranes) of red blood cells, the source of the first known member of the class]

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

References in periodicals archive ?

Other significantly mutated genes included lysine (K)--specific methyltransferase 2C (KMT2C), ataxia telangiectasia mutation (ATM), FAT atypical cadherin 1 (FAT1), CREB-binding protein (CREBBP), ERBB2, spectrin alpha non-erythrocytic 1 (SPTAN1), and lysine (K)--specific methyltransferase 2A (KMT2A), which were involved in the regulation of cell proliferation, differentiation, and genetic stability.

Bladder Cancer in the Genomic Era

Another two SNPs were located on the positions of 1.39 Mb and 2.71 Mb of chromosome 8 respectively, with the first SNP locating on the 14th intron of calmodulin regulated spectrin associated protein family member 2 (CAMSAP2) and the other locating on the 4th intron of potassium sodium-activated channel subfamily T member 2 (KCNT2).

Genome wide association study on feed conversion ratio using imputed sequence data in chickens

This stability is affected from different factors such as oxidative stress mediated lipid peroxidation, protein carbonylation, loss of spectrin which is the major mechanical support mesh of erythrocyte cell membrane and etc.

HOW LONG-TERM INTAKE OF SODIUM FLUORIDE (NAF) IN DIFFERENT DOSES AND 7,12 DIMETHYLBENZ(A)ANHTRACENE (DMBA) AFFECT THE ERYTHROCYTE PARAMETERS IN RATS?

Effects of age on fibre structure, ultrastructure and expression of desmin and spectrin in fast- and slow-twitch rat muscles.

Sarcomere Structure: The Importance of Desmin Protein in Muscle Atrophy/ Estructura de Sarcomera: La Importancia de Proteina Desmina en Atrofia Muscular

Native PAGE of isolated spectrin and structural analysis by limited digestion with trypsin indicated the presence of mutant spectrin [[alpha].sup.1/74].

Neonatal haemolytic anaemia--a diagnostic approach to red cell membrane disorders

The primary lesion is reduced deformability of erythrocytes due to defects in the membrane protein ankyrin, spectrin, or protein 4.2 (1).

Anesthetic Management with Total Intravenous Anesthesia in Hereditary Spherocytosis: A Case Report: Herediter Sferositoz'da Total Intravenoz Anestezi ile Anestezi Yonetimi

Nesprins (nuclear envelope spectrin repeat proteins) together with SUN proteins are central components of the NE.

Nesprin-2 Interacts with Condensin Component SMC2

Beck, "A role for the spectrin superfamily member Syne-1 and kinesin II in cytokinesis," Journal of Cell Science, vol.

Whole Exome Sequencing Uncovers Germline Variants of Cancer-Related Genes in Sporadic Pheochromocytoma