phenobarbital


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phe·no·bar·bi·tal

(fē′nō-bär′bĭ-tôl′, -tăl′)
n.
A long-acting barbiturate, C12H12N2O3, used medicinally as a sedative, hypnotic, and anticonvulsant, sometimes in the form of its sodium salt.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

phenobarbital

(ˌfiːnəʊˈbɑːbɪtəl) or

phenobarbitone

n
(Pharmacology) a white crystalline derivative of barbituric acid used as a sedative for treating insomnia and as an anticonvulsant in epilepsy. Formula: C12H12N2O3
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

phe•no•bar•bi•tal

(ˌfi noʊˈbɑr bɪˌtɔl, -ˌtæl, -nə-)

n.
a white, crystalline powder, C12H12N2O3, used as a sedative, a hypnotic, and as an antispasmodic in epilepsy.
[1915–20]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun 1. phenobarbital - a long-acting barbiturate used as a sedative
barbiturate - organic compound having powerful soporific effect; overdose can be fatal
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

phe·no·bar·bi·tal

n. fenobarbital, hipnótico, sedante, nombre comercial Luminal.
English-Spanish Medical Dictionary © Farlex 2012

phenobarbital

n fenobarbital m
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
The most commonly prescribed first-line medication is phenobarbital, although this is slowly changing.
In addition, the baby was treated with phenobarbital, a sedative to help him settle.
A girl aged six months was hospitalized because of resistant seizures and was discharged with phenobarbital and carbamazepine therapy.
Their follow-up study, published in the Journal of Feline Medicine and Surgery, compared levetiracetam, used to treat certain forms of epilepsy in humans, with the older drug phenobarbital.
In addition, icv montelukast prevents PTZ-induced blood-brain barrier (BBB) disruption and leukocyte infiltration (10), and potentiates the anticonvulsant effect of phenobarbital on PTZ seizures and decreases sedation, a major side effect of phenobarbital (11).
It is metabolized into phenobarbital and phenylethylmalonamide (PEMA).
Affected individuals do not respond to Phenobarbital therapy, need prolonged hours of intensive phototherapy, exchange transfusions and, without liver transplantation, usually die in infancy from kernicterus.
She had a medical history of Epilepsy treated by Phenobarbital since she was 16.
For drugs with >2 doses a day and/or long half-lives, these requirements were much too stringent for instrument performance (desirable CV phenobarbital [less than or equal to]1%).
In over 30 years of practice, I have found that the old migraine drug Bellergal-S (belladonna, ergotamine, and phenobarbital) works very well to relieve vasomotor symptoms and insomnia.

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