Ward, M.D., M.P.H., from the National Institute of Arthritis and Musculoskeletal and Skin Diseases in Bethesda, Maryland, and colleagues conducted updated systematic literature reviews for 20 clinical questions on
pharmacologic treatment addressed in previous guidelines and for 26 new questions on
pharmacologic treatment, treat-to-target strategy, and use of imaging.
They cover basic principles: basic principles of chronic pain in the primary care setting, and special populations; psychiatric disorders and pain; fundamentals of pain history, physical exam, and assessment; chronic pain treatment: non-pharmacologic therapies and
pharmacologic therapies.
The Endocrine Society has released new guidelines on the
pharmacologic treatment of osteoporosis in postmenopausal women.
The findings, published in the Journal of Alternative and Complementary Medicine, provide support for the use of yoga-based interventions as an alternative or supplement to
pharmacologic treatments for depression.
NEW ORLEANS -- In a new guideline for the
pharmacologic management of osteoporosis, bisphosphonates have been identified as the first-line therapy with denosumab (Prolia) listed as an acceptable alternative that is particularly well suited for high-risk patients, according to a presentation at the annual meeting of the Endocrine Society.
SAN DIEGO -- In critically ill patients receiving
pharmacologic thromboprophylaxis, adjunct intermittent pneumatic compression (IPC) had no effect on the rates of lower-limb deep vein thrombosis (DVT), according to a new trial.
Studies of
pharmacologic therapies ranged from 9 trials of benzodiazepines to 70 trials of NSAIDs.
Pharmacologic thromboprophylaxis was used in only 24.4% of patients (n=30).
Initiated in 2013, this collaboration leverages Ra Pharma's Extreme Diversity platform aimed at producing macrocyclic peptides that have the diversity and specificity of antibodies, while retaining the
pharmacologic attributes of small molecules.
"These bottlenecks include poor islet survival and significant side-effects, many associated with obligate
pharmacologic immunosuppression...
Privately-held Seraxis, incorporated in Singapore and in the U.S., used proprietary technologies to develop: a cell therapy that functions shortly after transplantation in diabetic animals and; a device, SeraGraft, that safely protects these human pancreas cells from the immune system of animal hosts without need for
pharmacologic immunosuppression.