Patients without soft tissue extension or necrosis and patients with a solitary periurethral, scrotal or perianal abscess were excluded from the study.
First, we histologically examined all prostate lobes and the periurethral prostatic ducts for pathologic lesions in two cohorts of rats, one exposed continuously from implantation through adulthood and the other developmentally exposed from implantation through PND 21, the "stop-dose" BPA cohort.
Although the possibility of a small scratch that had gone unnoticed cannot be ruled out, an alternative explanation could be a periurethral contamination of the patient after handling his dog, followed by colonization of the urethra and subsequent migration of the bacteria to the bladder.
Two mL of Polyacrylamide hydrogel was injected under neurolept sedation in all women using a specialised sheath and rigid pediatric cystoscopy into 3 to 4 sites in the proximal urethra as previously described; we utilised the standard technique of periurethral injection with the goal of creating "mounds" that increased the coaptation of the urethra (8).
Postoperative success rates can be further improved by better patient selection criteria, for example by excluding patients with severe periurethral fibrosis and scarring due to previous radiation therapy and surgery for recurrent stricture disease.
Although the mainstay in the management of necrotizing soft tissue infection is wide often repeated debridement, the patient presented here underwent incision and debridement of the necrotic periurethral tissue and his urethra largely remained intact.