nitrofurantoin


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ni·tro·fur·an·to·in

(nī′trō-fyo͝o-răn′tō-ĭn)
n.
A derivative of nitrofuran, C8H6N4O5, used to treat bacterial infections of the urinary tract.

[nitrofuran + (hydan)toin, one of its constituents; see diphenylhydantoin.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun 1. [画像:nitrofurantoin - derivative of nitrofuran used as an antibacterial medicine (trade name Macrodantin) effective against a broad range of Gram-positive and Gram-negative bacteria]nitrofurantoin - derivative of nitrofuran used as an antibacterial medicine (trade name Macrodantin) effective against a broad range of Gram-positive and Gram-negative bacteria; used to treat infections of the urinary tract
antibacterial, antibacterial drug, bactericide - any drug that destroys bacteria or inhibits their growth
nitrofuran - derivative of furan used to inhibit bacterial growth
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
ENPNewswire-July 29, 2019--CMA alleges breach of competition law on Nitrofurantoin NPA reaction
Although other antibiotics, such as fosfomycin, are more effective toward ESBL, nitrofurantoin is still adequate in treating uncomplicated ESBL E.
Bu diskler sirasiyla ampisilin (2 [micro]g), ampisilin (10 [micro]g), vankomisin (30 [micro]g), linezolid (10 [micro]g), linezolid (30 [micro]g), nitrofurantoin (100 [micro]g), nitrofurantoin (300 [micro]g), norfloksasin (10 [micro]g), teikoplanin (30 [micro]g) (Bioanalyse, Ankara, Turkiye); gentamisin (30 [micro]g), gentamisin (120 [micro]g), streptomisin (300 [micro]g) ve kinupristin-dalfopristin (15 [micro]g) (Oxoid, Basingstoke, Birlesik Krallik) ve vankomisin (5 [micro]g) (Becton Dickinson, Sparks, MD, ABD) olarak belirlenmistir.
Your kind of cystitis has been the subject of many studies and the latest advice for treating it is first a trial of a five-day course of an antibiotic called nitrofurantoin.
Antibiotics against which sensitivity was tested included ampicillin (10 [micro]g), amoxyclav (20 [micro]g/10 [micro]g), ceftazidime (30 [micro]g), ceftriaxone (30 [micro]g), aztreonam (30 [micro]g), gentamicin (10 [micro]g), amikacin (30 [micro]g), ciprofloxacin (5 [micro]g), co-trimoxazole (25 [micro]g), norfloxacin (10 [micro]g), nitrofurantoin (300 [micro]g), piperacillin-tazobactam (100 [micro]g/10 [micro]g) and meropenem (10 [micro]g).
MADRID--Five days of nitrofurantoin was significantly more effective than was a single large dose of fosfomycin in effecting both clinical and microbiological cure among women with uncomplicated lower urinary tract infections, a randomized study has determined.
They found that five classes of oral antibiotics oral sulfas, cephalosporins, fluoroquinolones, nitrofurantoin, and broad-spectrum penicillins were associated with a diagnosis of kidney stone disease.
TUESDAY, April 24, 2018 (HealthDay News) -- Five-day nitrofurantoin is associated with increased likelihood of clinical and microbiological resolution compared with single-dose fosfomycin among women with lower urinary tract infection (UTI), according to a study published online April 22 in the Journal of the American Medical Association.
Nitrofurantoin and trimethoprim-sulfamethoxazole have study data indicating their teratogenicity, and ACOG has recommended against use of these 2 agents in the first trimester of pregnancy unless other antibiotics are unlikely to be effective.
Because of the potential risk for birth defects, including anencephaly, heart defects, and orofacial clefts, associated with use of sulfonamides and nitrofurantoin during pregnancy (3), a 2011 committee opinion from the American College of Obstetricians and Gynecologists (ACOG) recommended that sulfonamides and nitrofurantoin may be prescribed in the first trimester of pregnancy only when other antimicrobial therapies are deemed clinically inappropriate (4).
There are three urinary germicides: methenamine, methylene blue, and nitrofurantoin. Methenamine is available as methenamine mandelate (molecular weight abut 292) and methenamine hippurate (molecular weight about 319).

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