imidazole


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im·id·az·ole

(ĭm′ĭ-dăz′ōl′)
n.
1. An organic crystalline base, C3H4N2, that is an inhibitor of histamine.
2. Any of various derivatives of this compound, which often have antifungal, anthelmintic, or antibiotic properties.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

imidazole

(ˌɪmɪdˈæzəʊl; -ɪdəˈzəʊl)
n
1. (Elements & Compounds) Also called: glyoxaline or iminazole a white crystalline basic heterocyclic compound; 1,3-diazole. Formula: C3H4N2
2. (Elements & Compounds) any substituted derivative of this compound
[C19: from imide + azole]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

im•id•az•ole

(ˌɪm ɪdˈæz oʊl, -ɪd əˈzoʊl)

n.
a colorless, crystalline, water-soluble, heterocyclic compound, C3H4N2, used chiefly in organic synthesis.
[1890–95; imide + azole]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun 1. imidazole - an organic base C3H4N2; a histamine inhibitor
alkali, base - any of various water-soluble compounds capable of turning litmus blue and reacting with an acid to form a salt and water; "bases include oxides and hydroxides of metals and ammonia"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
imidazole
References in periodicals archive ?
[58.] Hardy E, Pupo E, Castellanos-Serra L, Reyes J, Fernandez-Patron C (1997) Sensitive reverse staining of bacterial lipopolysaccharides on polyacrylamide gels by using zinc and imidazole salts.
Lipopolysaccharide (LPS) and protein-LPS complexes: detection and characterization by gel electrophoresis, mass spectrometry and bioassays
Imidazole Dipeptides: Chemistry, Analysis, Function and Effects
Imidazole Dipeptides: Chemistry, Analysis, Function and Effects
The resin was pre-equilibrated with 10 volumes of 20 mmol l-1 Tris-HCl pH 8.5, followed by 10 volumes of a solution containing 50 mmol [1.sup.-1] Tris-HCl pH 8.5, 0.3 mol l_l NaCl, and 10 mmol [1.sup.-1] imidazole. After the filtered supernatant was loaded, the column was washed with 50 ml of a solution containing 50 mmol [1.sup.-1] Tris-HCl pH 8.5, 0.3 mol [1.sup.-1] NaCl, and 20 mmol [1.sup.-1] imidazole until the OD280 (wavelength used to measure protein concentration, with absorbance at 280 nm) of the washing solution approached zero.
Two activin type 2B receptors from sea bream function similarly in vitro
Pariser discussed is luliconazole (Luzu), a prescription topical imidazole that is available as a 1% cream.
New antifungals show promise for tinea pedis: luliconazole and naftifine offer easier treatment regimens and higher rates of successful outcomes
Etomidate is the only imidazole among general anesthesia inducing drugs and has the most favorable therapeutic effect following single bolus administration.
Underlying Mechanisms of Memory Deficits Induced by Etomidate Anesthesia in Aged Rat Model: Critical Role of Immediate Early Genes
Histamine + [O.sub.2] + [H.sub.2]0 [??](DAO) [??] Imidazole acetaldehyde +N[H.sub.3] + [H.sub.2][0.sub.2]
The nutri-genomic impact on histamine metabolism
One of the more promising alternatives is imidazole and its derivatives.
The effect of magnetic field on corrosion inhibitor of copper in 0.5m NaCl solution
Imidazole an alkaloid from plant secondary metabolites, is an important component of antifungal, anti protozoal, anti helminthic and anti cancer medications.
Toxicological evaluation of imidazole following direct exposure to bone marrow mesenchymal stem cells
These preparations belong to the Imidazole group and are fungicidal, rupturing the cell membrane and killing the cell; they are not generally well absorbed as a systemic treatment.
This is an evaluation of dermatophyte microorganisms, which have particular relevance in podiatry
* MICONAZOLE NITRATE- An imidazole antifungal agent, commonly applied topically to the skin or to mucous membranes to cure fungal infections, and a skin conditions.
McKinley Resource Incorporated
Wheatish light brown crystals, Yield (2.2 g, 85%), m.p 200-204[degrees]C, IR (KBr, [v.sub.max] in [cm.sup.-1]): 3435 (-NH), 2922 (=C-H), 1683 (C=N), 1620 (C=C), [sup.1]H NMR (DMSO-[d.sub.6], 400 MHz) [delta] ppm: 2.5 (s, 2H, -C[H.sub.2]), 72-74 (d, 1H, -C=CH, [J.sub.H-H] = 16.4 Hz), 75-73 (m, 4 aryl, 3 phenyl protons), 7.8-8.0 (d, 1H, -CH=C, [J.sub.H-H] = 16.4 Hz), 10.0 (s, 1H, -NH of benzimidazole), [sup.13]C NMR (DMSO-[d.sub.6], 100 MHz) [delta] ppm: 102.29, 108.54, 109, 122, 124, 128, 130, 132, 134, 138, 148, 152 (1 dioxymethylene carbon, 6 aryl carbons, 6 phenylic carbons, 2 vinylic carbons and 1 imidazole quaternary carbon), MS (m/z): 265.10 ([M.sup.+*]), Anal.
Glycerol containing triacetylborate mediated syntheses of novel 2-heterostyryl benzimidazole derivatives: a green approach