The occipital hyperactivation observed in PI patients fits with the hyperarousal theory of insomnia [37], positing a hypersensibility to external stimuli which might be driven by an overactivity of visual brain regions in patients.
Such infections have been reported in some studies and are attributable to superinfections, predisposing factors such as asthma, increasing hypersensibility to one of the infections or to behaviors that MP may have as commensal flora in immunocompetent patients [45], which is important to keep in mind when interpreting the results as well as when doing the processes of therapeutic intervention in the patient.