Table 1 Medications associated with serotonin syndrome Class Medication(s) Antidepressants Selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, tricyclic antidepressants Monoamine oxidase inhibitors Trazodone Mirtazapine Triptans Almotriptan,
eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan Anxiolytics Buspirone Antiemetics Ondansetron, granisetron, metoclopramide Herbal supplements St.
(21) Triptans are superior to placebo in achieving a pain-free state at 2 and 24 hours after administration;
eletriptan has the most desirable outcome, with 68% of patients pain free at 2 hours and 54% pain free at 24 hours.
Serotonergic effects and extracellular brain levels of
eletriptan, zolmitriptan and sumatriptan in rat brain.
During his pharma tenure, he played a leadership role in the clinical development of Celebrex (celecoxib) and Relpax (
eletriptan).
Her medication list included Fioricet,
eletriptan, prednisone, hydrochloroquine, lansoprazole, ranitidine, phenobarbital, and polyethylene glycol.
Eletriptan vs sumatriptan: A double-blind placebo-controlled, multiple migraine attack study.
This class of medications includes naratriptan, rizatriptan,
eletriptan, sumatriptan, zolmitriptan, almotriptan, and frovatriptan.
The triptan drugs (e.g., sumatriptan, rizatriptan,
eletriptan, and almotriptan), which are used for more severe migraines, promote vasoconstriction and block pain pathways by activating certain serotonin receptors in cranial blood vessels (Bajwa 2012).
This therapeutic class comprises seven members, namely, sumatriptan, zolmitriptan, rizatriptan,
eletriptan, almotriptan, naratriptan, and the latest one "frovatriptan." All triptans share similar pharmacodynamics but each of them comprises a different pharmacokinetic profile which makes each of them a unique of its kind.
Prior to evaluation and treatment at the headache clinic, she had tried multiple regimens including, over-the-counter medications, combination acetaminophen, butalbital, and caffeine, oral contraceptive pills, amitriptyline, propranolol, verapamil, gabapentin, sumpatriptan, frovatriptan, rizatriptan and
eletriptan, without significant relief.
Specific triptans include naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), zolmitriptan (Zomig), almotriptan (Axert), frovatriptan (Frova) and
eletriptan (Relpax).
He was treated with a prednisone regimen, and he was also given
eletriptan for management of the acute attacks.