X-SCID


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Noun 1. X-SCID - SCID in male children resulting from mutation of a gene that codes for a protein on the surface of T cells that allows them to develop a growth factor receptor
SCID, severe combined immunodeficiency, severe combined immunodeficiency disease - a congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life
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References in periodicals archive ?
Eight infants with the disorder, called X-linked severe combined immunodeficiency (X-SCID), received an experimental gene therapy co-developed by National Institutes of Health scientists.
Gene Therapy Restores Immunity in Infants
In 2000 specialists researching his disease, funded by the charity Jeans for Genes, were ready to help a child suffering from x-Scid.
Brave little Rhys is star of the show
The Food and Drug Administration (FDA's) Cellular, Tissue and Gene Therapies Advisory Committee made the recommendation following a March 4 hearing called in response to a recent report a third child with X-SCID being treated with gene therapy had developed leukemia in a similar French study.
FDA panel recommends 2 US gene therapy trials proceed on limited basis
Ada-SCID affects both boys and girls and is more difficult to treat than X-SCID.
Scientists in gene therapy landmark
Rhys was born with severe combined immuno-deficiency (X-Scid), which meant the slightest contact with an infectious bug would have been fatal.
Birthday party for boy in a bubble
This led to break-throughs in treating several forms of this disorder, most notably in treating X-linked SCID (X-SCID) through use of a retrovirus to deliver the corrected gene into the patient's hematopoietic stem cells.
Guest editorial: the promise of gene therapy
This led to breakthroughs in treating several forms of this disorder, most notably in treating X-linked SCID (X-SCID) through use of a retrovirus to deliver the corrected gene into hematopoietic stem cells.
The promise of gene therapy
Seven children and one adult have been treated for X-SCID at Great Ormond Street.
Breakthrough brings fresh hope to 'bubble babies' in Britain

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