This study will also inform clinical expansion into adjacent opportunities in neurological conditions such as
epileptiform disorders and Parkinson's.
The epilepsy photosensitivity model includes study participants who have reproducible generalized
epileptiform discharges on electroencephalogram stimulated by flashing lights within a range of frequencies called a photoparoxysmal response.
No seizure or interictal
epileptiform activity appeared during those episodes.
Interictal EEG changes showed bilateral temporal
epileptiform activities with decreased baseline activity.
Electroencephalograph (EEG) did not show
epileptiform discharges, but it is not so unreasonable since there are almost 10-20% epileptic patients have normal EEG presentation.
The late forms of chronic seizures can appear as tonic seizures, myoclonic jerks, infantile spasms, multifocal
epileptiform activity, or hypsarrhythmia on EEG.
Electroencephalography showed right temporal focal-onset secondary generalized
epileptiform abnormality.
EEG###Day 1: Moderate diffuse encephalopathy worse on the right side, frequent
epileptiform discharges from right temporal region
Focal
epileptiform discharges were seen in 40 (37.4%) patients followed by generalized
epileptiform discharges in 12 patients.
His neurological condition did not improve with EEG persistently showing frequent generalized
epileptiform discharges (Figure 1(d)).