clomiphene citrate

Geir Helgemo, who is Norwegian but represents Monaco in bridge events, tested positive for synthetic testosterone and female fertility drug clomifene at a World Bridge Series event in Orlando, Florida last September, the federations aid Friday.

Chemical [EC.sub.20] (M) Individual dose in mix III at [10.sup.-5] M BPA 1.30 x [10.sup.-6] 5.34 x [10.sup.-7] Clomifene 6.21 x [10.sup.-7] 2.55 x [10.sup.-7] Ketoconazole 5.98 x [10.sup.-7] 2.46 x [10.sup.-7] Valproic acid 5.03 x [10.sup.-7] 2.07 x [10.sup.-7] BPS 8.64 x [10.sup.-6] 3.55 x [10.sup.-6] Chlordecone 5.92 x [10.sup.-6] 2.43 x [10.sup.-6] Imazalil 6.70 x [10.sup.-6] 2.76 x [10.sup.-6] Theophylline 3.67 x [10.sup.-8] 1.69 x [10.sup.-8] Mixture III effect 53% reduction in the testosterone production Note: [EC.sup.20] is the concentration (M, mol/L) of each substance associated with a 20% reduction of testosterone production.

clomifene (British spelling) is now a generic medication in most markets; it is unlikely that a drug company would pursue FDA approval for use in men now because of limited profit incentive." (58) They correctly add, however, that a single isomer of clomiphene is under phase III trials for men.