Last year, Breckenridge received approval for Azelastine HC1 Nasal Solution (Nasal Spray), a generic version of
Astelin, marketed by Meda Pharmaceuticals.
Thus, particularly antihistamines, such as azelastine, even in nasal spray form, continue to cause sedation/somnolence and nasal burning occasionally (
Astelin patient information).
Although some patients with these conditions respond to the usual rhinitis medications, most will respond best to
Astelin or Patanase, the only two antihistamine nasal sprays that, ironically, work well on non-allergic rhinitis.
Second-generation drugs developed later, including loratadine (Claritin), fexofenadine (A llegra), cetirizine (Zyrtec), and azelastine (
Astelin Nasal Spray), are less likely to cause these effects.
Currency effects and generic competition for the
Astelin and Optivar products are the most important reasons for decreased sales compared with last year.
Meda's sales decreased 12% year-on-year to SEK11.571bn in 2010, mainly pulled down by negative currency effects and generic competition for nasal spray
Astelin and eye drops Optivar.
Human data are limited for fexofenadine (Allegra) and azelastine (
Astelin) in pregnancy
In a letter to Meda, the FDA said a waiting room sign touting
Astelin nasal spray for allergies overstates effectiveness and "omits and minimizes important risk information." The sign said "Allergic to house cleaning?" and pitched
Astelin as a treatment.
Among its advantages is less of a taste problem, compared with the last similar product approved in 1996, azelastine HCl (
Astelin nasal spray, Meda Pharmaceuticals Inc.).
Among its other advantages is less of a taste problem, compared with the last similar product approved in 1996, azelastine HCl (
Astelin nasal spray, Meda Pharmaceuticals Inc.).
Works
Astelin (azelastine) Prescription fast but with more side effects than long-acting oral antihistamines.
(20.)
Astelin (Azelastine product information package insert).