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IMP21 Imp21p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854652, updated on 6-Jul-2025

In addition, your package will include a detailed data report in both TSV and JSONL formats.

Official Symbol
IMP21
Official Full Name
Imp21p
Primary source
SGD:S000001416
Locus tag
YIL154C
See related
AllianceGenome:SGD:S000001416; FungiDB:YIL154C; VEuPathDB:YIL154C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
IMP2
Summary
Enables transcription coactivator activity. Involved in regulation of transcription by RNA polymerase II. Located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See IMP21 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (53981..55021, complement)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes

Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. IMP2, a nuclear gene controlling the mitochondrial dependence of galactose, maltose and raffinose utilization in Saccharomyces cerevisiae. Donnini C, et al. Yeast, 1992 Feb. PMID 1561839
  2. Isolation and characterization of Saccharomyces cerevisiae mutants with enhanced resistance to the anticancer drug bleomycin. Aouida M, et al. Curr Genet, 2004 May. PMID 15007625
  3. The Saccharomyces cerevisiae IMP2 gene encodes a transcriptional activator that mediates protection against DNA damage caused by bleomycin and other oxidants. Masson JY, et al. Mol Cell Biol, 1996 May. PMID 8628275, Free PMC Article
  4. IMP2, a gene involved in the expression of glucose-repressible genes in Saccharomyces cerevisiae. Lodi T, et al. Microbiology (Reading), 1995 Sep. PMID 7496532
  5. The transcriptional activator Imp2p maintains ion homeostasis in Saccharomyces cerevisiae. Masson JY, et al. Genetics, 1998 Jun. PMID 9611200, Free PMC Article

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. YAP1 overexpression rescues the imp2Delta mutant from bleomycin toxicity by triggering Tpo1 expression to expel the drug.
    Title: Upregulation of the Saccharomyces cerevisiae efflux pump Tpo1 rescues an Imp2 transcription factor-deficient mutant from bleomycin toxicity.
Products Interactant Other Gene Complex Source Pubs Description
Preferred Names
Imp21p
NP_012112.3
  • Transcriptional activator involved in maintenance of ion homeostasis; also involved in protection against DNA damage caused by bleomycin and other oxidants; contains a C-terminal leucine-rich repeat

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    53981..55021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179502.3 → NP_012112.3 TPA: Imp21p

    See identical proteins and their annotated locations for NP_012112.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVD3, P32351
    UniProtKB/TrEMBL
    A6ZVC2, B3LU01, B5VKF8, G2WFZ8, N1P0N6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32351.2

Gene LinkOut

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