Lilrb4b MGI Mouse Gene Detail - MGI:102702 - leukocyte immunoglobulin-like receptor, subfamily B, member 4B

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Lilrb4b Gene Detail
Summary
  • Symbol
    Lilrb4b
  • Name
    leukocyte immunoglobulin-like receptor, subfamily B, member 4B
  • Synonyms
    gp49, Gp49a, Lilr4b
  • Feature Type
    protein coding gene
  • IDs
    MGI:102702
    NCBI Gene: 14727
  • Alliance
  • Transcription Start Sites
    27 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:51356757-51362417 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 25.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    486 from dbSNP Build 142
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J no annotation
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    LILRB4, leukocyte immunoglobulin like receptor B4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LILRB4, leukocyte immunoglobulin like receptor B4
  • Synonyms
    B4, CD85K, ILT-3, ILT3, LIR-5, LIR5
  • Links
    NCBI Gene ID: 11006
    neXtProt AC: NX_Q8NHJ6
    UniProt: Q8NHJ6

  • Chr Location
    19q13.42; chr19:54643889-54670359 (+) GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

Phenotype Overview
Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.
adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

Expression Overview
GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.
  • Blue cells = expressed in wild-type.
    Gray triangles = other expression annotations only
    (e.g. absence of expression or data from mutants).
early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 14727 NCBI Gene Model | MGI Sequence Detail 5661 C57BL/6J ± kb
    transcript NM_001291892 RefSeq | MGI Sequence Detail 1430 C57BL/6
    polypeptide Q61450 UniProt | EBI | MGI Sequence Detail 303 Not Applicable
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 26
      Genomic 2
      cDNA 24

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGD-MRK-19606, MGI:6718869
    References
    more
    • Summaries
      All 38
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    TSS for Lilrb4b:
    (View these features in JBrowse)
    Transcription Start Site Location Distance from Gene 5'-end
    Tssr93233 Chr10:51356909-51356930 (+) 163 bp
    Tssr93234 Chr10:51356935-51356946 (+) 184 bp
    Tssr93235 Chr10:51357228-51357240 (+) 477 bp
    Tssr93236 Chr10:51357714-51357752 (+) 976 bp
    Tssr93237 Chr10:51357753-51357770 (+) 1,005 bp
    Tssr93238 Chr10:51357777-51357787 (+) 1,025 bp
    Tssr93239 Chr10:51357802-51357816 (+) 1,052 bp
    Tssr93240 Chr10:51357819-51357838 (+) 1,072 bp
    Tssr93241 Chr10:51357841-51357848 (+) 1,088 bp
    Tssr93242 Chr10:51357881-51357894 (+) 1,131 bp
    Tssr93243 Chr10:51358674-51358709 (+) 1,935 bp
    Tssr93244 Chr10:51358940-51358980 (+) 2,203 bp
    Tssr93245 Chr10:51359463-51359516 (+) 2,733 bp
    Tssr93246 Chr10:51359679-51359701 (+) 2,933 bp
    Tssr93247 Chr10:51359725-51359744 (+) 2,978 bp
    Tssr93248 Chr10:51359773-51359785 (+) 3,022 bp
    Tssr93249 Chr10:51359918-51359951 (+) 3,178 bp
    Tssr93250 Chr10:51360405-51360412 (+) 3,652 bp
    Tssr93251 Chr10:51360444-51360473 (+) 3,702 bp
    Tssr93252 Chr10:51360547-51360568 (+) 3,801 bp
    Tssr93253 Chr10:51360742-51360764 (+) 3,996 bp
    Tssr93254 Chr10:51360869-51360897 (+) 4,126 bp
    Tssr93255 Chr10:51361096-51361115 (+) 4,349 bp
    Tssr93256 Chr10:51361208-51361218 (+) 4,456 bp
    Tssr93257 Chr10:51361571-51361603 (+) 4,830 bp
    Tssr93258 Chr10:51361806-51361843 (+) 5,068 bp
    Tssr93259 Chr10:51361848-51361858 (+) 5,096 bp
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support. last database update
    12/17/2024
    MGI 6.24 The Jackson Laboratory
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