C. parapsilosis ERG11/CPAR2_303740 Literature Guide

Reference	Species	Other Genes Addressed
*Bartalucci C, et al.* (2025)** Clinical impact of fluconazole-resistant Candida parapsilosis: a narrative review. Future Microbiol :1-10 CGD Papers Entry Pubmed Entry	C. parapsilosis	\|FKS1
*Kurt O, et al.* (2025)** [Investigation of ERG11 and MRR1 Resistance Genes in Candida parapsilosis Isolates]. Mikrobiyol Bul 59(3):376-385 CGD Papers Entry Pubmed Entry	C. parapsilosis	\|MRR1
*Hartuis S, et al.* (2024)** Precise genome editing underlines the distinct contributions of mutations in ERG11, ERG3, MRR1, and TAC1 genes to antifungal resistance in Candida parapsilosis. Antimicrob Agents Chemother :e0002224 CGD Papers Entry Pubmed Entry	C. parapsilosis	\|ERG3 \|MRR1 \|TAC1
*Karthika K, et al.* (2024)** Standardization of polymerase chain reaction for detection of fluconazole resistance targeting Y132F mutation in ERG11 gene in Candida parapsilosis. Curr Med Mycol 10 CGD Papers Entry Pubmed Entry
*Ning YT, et al.* (2024)** Emergence of multiple fluconazole-resistant Candida parapsilosis sensu stricto clones with persistence and transmission in China. J Antimicrob Chemother 79(1):128-133 CGD Papers Entry Pubmed Entry	C. parapsilosis	\|MRR1 \|TAC1
*Ozturk S, et al.* (2024)** Rapid Tetra-Primer Amplification Refractory Mutation System-Polymerase Chain Reaction Protocol for Detection of Y132F Mutation in Fluconazole Resistant Candida parapsilosis. Microb Drug Resist CGD Papers Entry Pubmed Entry
*Alkhars N, et al.* (2023)** Antifungal Susceptibility of Oral Candida Isolates from Mother-Infant Dyads to Nystatin, Fluconazole, and Caspofungin. J Fungi (Basel) 9(5) CGD Papers Entry Pubmed Entry	C. albicans	\|CDR2 \|GSC1 \|GSL1
C. parapsilosis	\|FKS1
C. dubliniensis	\|CDR2
*Byun JH, et al.* (2023)** Detection and Characterization of Two Phenotypes of Candida parapsilosis in South Korea: Clinical Features and Microbiological Findings. Microbiol Spectr :e0006623 CGD Papers Entry Pubmed Entry
*Ceballos-Garzon A, et al.* (2023)** Emergence and circulation of azole-resistant C. albicans, C. auris and C. parapsilosis bloodstream isolates carrying Y132F, K143R or T220L Erg11p substitutions in Colombia. Front Cell Infect Microbiol 13:1136217 CGD Papers Entry Pubmed Entry	C. auris	\|TAC1b
C. albicans	\|TAC1
C. parapsilosis	\|MRR1
*Diaz-Garcia J, et al.* (2023)** Trends in antifungal resistance in Candida from a multicenter study conducted in Madrid (CANDIMAD study): fluconazole-resistant C. parapsilosis spreading has gained traction in 2022. Antimicrob Agents Chemother 67(11):e0098623 CGD Papers Entry Pubmed Entry
*Doorley LA, et al.* (2023)** Mutations in TAC1 and ERG11 are major drivers of triazole antifungal resistance in clinical isolates of Candida parapsilosis. Clin Microbiol Infect CGD Papers Entry Pubmed Entry	C. parapsilosis	\|CDR1
*Hubler CM, et al.* (2023)** Recent increase in fluconazole-nonsusceptible Candida parapsilosis in a global surveillance with the expansion of the Erg11 Y132F genotype and a rapid detection method for this alteration. Diagn Microbiol Infect Dis 106(3):115957 CGD Papers Entry Pubmed Entry
*Khalifa HO, et al.* (2023)** Antifungal Resistance and Genotyping of Clinical Candida parapsilosis Complex in Japan. J Fungi (Basel) 10(1) CGD Papers Entry Pubmed Entry	C. parapsilosis	\|FKS1
*McTaggart LR, et al.* (2023)** First Canadian report of transmission of fluconazole-resistant Candida parapsilosis within two hospital networks confirmed by genomic analysis. J Clin Microbiol :e0116123 CGD Papers Entry Pubmed Entry	C. parapsilosis	\|CDR1
*Ngo TMC, et al.* (2023)** Azole non-susceptible C. tropicalis and polyclonal spread of C. albicans in Central Vietnam hospitals. J Infect Dev Ctries 17(4):550-558 CGD Papers Entry Pubmed Entry
*Presente S, et al.* (2023)** Hospital Clonal Outbreak of Fluconazole-Resistant Candida parapsilosis Harboring the Y132F ERG11p Substitution in a French Intensive Care Unit. Antimicrob Agents Chemother :e0113022 CGD Papers Entry Pubmed Entry
*Saiprom N, et al.* (2023)** Characterization of Virulence Factors in Candida Species Causing Candidemia in a Tertiary Care Hospital in Bangkok, Thailand. J Fungi (Basel) 9(3) CGD Papers Entry Pubmed Entry
*Xie F, et al.* (2023)** Novel antifungal triazoles with alkynyl-methoxyl side chains: Design, synthesis, and biological activity evaluation. Eur J Med Chem 257:115506 CGD Papers Entry Pubmed Entry	C. albicans	\|CDR1 \|MDR1
*Zeeshan M, et al.* (2023)** Fluconazole-resistant Candida parapsilosis complex candidemia and analysis of mutations in the ERG11 gene from Pakistan. Mycoses CGD Papers Entry Pubmed Entry
*Alcoceba E, et al.* (2022)** Fluconazole-resistant Candida parapsilosis clonally related genotypes: first report proving the presence of endemic isolates harbouring the Y132F ERG11 gene substitution in Spain. Clin Microbiol Infect CGD Papers Entry Pubmed Entry
*Arastehfar A, et al.* (2022)** Candidemia Among Coronavirus Disease 2019 Patients in Turkey Admitted to Intensive Care Units: A Retrospective Multicenter Study. Open Forum Infect Dis 9(4):ofac078 CGD Papers Entry Pubmed Entry
*Bilal H, et al.* (2022)** Distribution and antifungal susceptibility pattern of Candida species from mainland China: A systematic analysis. Virulence 13(1):1573-1589 CGD Papers Entry Pubmed Entry	C. auris	\|ERG3
C. albicans	\|ERG3 \|ERG4 \|MRR1
C. glabrata	\|ERG3 \|ERG4
C. parapsilosis	\|ERG3 \|ERG4 \|MRR1
*Branco J, et al.* (2022)** Clinical azole cross-resistance in Candida parapsilosis is related to a novel MRR1 gain-of-function mutation. Clin Microbiol Infect CGD Papers Entry Pubmed Entry	C. parapsilosis	\|CDR1B \|MDR1 \|MRR1
*Daneshnia F, et al.* (2022)** Determinants of fluconazole resistance and echinocandin tolerance in C. parapsilosis isolates causing a large clonal candidemia outbreak among COVID-19 patients in a Brazilian ICU. Emerg Microbes Infect :1-33 CGD Papers Entry Pubmed Entry	C. auris	\|FKS1
C. parapsilosis	\|CDR1
*Daneshnia F, et al.* (2022)** Determinants of fluconazole resistance and the efficacy of fluconazole and milbemycin oxim combination against Candida parapsilosis clinical isolates from Brazil and Turkey. Front Fungal Biol 3:906681 CGD Papers Entry Pubmed Entry	C. parapsilosis	\|CDR1 \|MDR1 \|MRR1 \|TAC1 \|UPC2
*Diaz-Garcia J, et al.* (2022)** Candida Genotyping of Blood Culture Isolates from Patients Admitted to 16 Hospitals in Madrid: Genotype Spreading during the COVID-19 Pandemic Driven by Fluconazole-Resistant C. parapsilosis. J Fungi (Basel) 8(11) CGD Papers Entry Pubmed Entry
*Diaz-Garcia J, et al.* (2022)** Evidence of Fluconazole-Resistant Candida parapsilosis Genotypes Spreading across Hospitals Located in Madrid, Spain and Harboring the Y132F ERG11p Substitution. Antimicrob Agents Chemother :e0071022 CGD Papers Entry Pubmed Entry
Escribano P and Guinea J (2022) Fluconazole-resistant Candida parapsilosis: A new emerging threat in the fungi arena. Front Fungal Biol 3:1010782 CGD Papers Entry Pubmed Entry
*Hare RK, et al.* (2022)** Candidemia among Hospitalized Pediatric Patients Caused by Several Clonal Lineages of Candida parapsilosis. J Fungi (Basel) 8(2) CGD Papers Entry Pubmed Entry	C. parapsilosis	\|FKS1
*Kim TY, et al.* (2022)** Evolution of Fluconazole Resistance Mechanisms and Clonal Types of Candida parapsilosis Isolates from a Tertiary Care Hospital in South Korea. Antimicrob Agents Chemother :e0088922 CGD Papers Entry Pubmed Entry	C. parapsilosis	\|CDR1 \|MRR1

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