C. albicans ISU1/C7_01760C Summary

Last curated 2017年09月20日
See the Literature Guide for most recent publications.

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Summary
Locus History Literature Gene Ontology Phenotype Homologs Protein
ISU1 BASIC INFORMATION [ View References ]
Standard Name ISU11
Systematic Name, Reference Strain C7_01760C_A (C. albicans SC5314)
Assembly 19/21 Identifier orf19.6548
Alias orf19.13901, orf6.52662 , IPF20648.12 , IPF11829.12 , Contig4-2620_00043 , CA31092 , CaJ7.01994 , CaO19_65485 , CaJ7_01995 , CaO19.65485 , CaO19.139015 , IPF118292 , orf19.6548, C7_01760C_B, C7_01760C
Feature Type ORF, Uncharacterized
Description Protein with similarity to NifU; possible role in iron-sulfur cluster biogenesis; induced in low iron; rat catheter biofilm induced; rat catheter and Spider biofilm induced (1, 6, 7)
Literature
Allele Name C7_01760C_B
Allelic Variation No allelic variation in feature
CUG Codons C7_01760C_A: 0
C7_01760C_B: 0
Systematic Names Used in Other Strains CAWG_05527 (C. albicans WO-1)
Orthologous genes in Candida species C. dubliniensis CD36 Ortholog(s) : Cd36_71600
C. parapsilosis CDC317 Ortholog(s) : CPAR2_702510
C. auris B8441 Ortholog(s) : B9J08_005097
C. glabrata CBS138 Ortholog(s) : CAGL0M02629g
View ortholog cluster : 19 genes among 19 Candida-related species/strains
Ortholog(s) in non-CGD species A. nidulans (AN4655) ; N. crassa (NCU05778) ; S. pombe (SPAC227.13c) ; S. cerevisiae (ISU1)
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JBrowse for feature C7_01760C_A

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GO Annotations View all ISU1 GO evidence and references

Molecular Function
Computational * 2 iron, 2 sulfur cluster binding (IEA with S. pombe: SPAC227.13c)
* iron-sulfur cluster binding (IEA with S. pombe: SPAC227.13c)
* iron-sulfur cluster chaperone activity (IEA with S. pombe: SPAC227.13c)

Biological Process
High-throughput * iron-sulfur cluster assembly (NAS)
Computational * [2Fe-2S] cluster assembly (IEA with S. pombe: SPAC227.13c)

Cellular Component
Manually curated * cellular_component unknown (ND)
Mutant Phenotype View all ISU1 Phenotype details and references
Large-scale survey
heterozygous null * cell size: decreased
* viable

null * inviable

repressible * vegetative growth: normal rate
* viable

Sequence Information Ca22chr7A_C_albicans_SC5314:377785 to 377222 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年01月21日 | Sequence: 2014年06月24日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to564377,785to377,2222016年01月21日2014年06月24日

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Maps & Displays
Sequence Information Ca22chr7A_C_albicans_SC5314:377785 to 377222 | JBrowse
Note: this feature is encoded on the Crick strand.
Allele Location
Allele C7_01760C_B 		Ca22chr7B_C_albicans_SC5314:377788 to 377225 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年01月21日 | Sequence: 2014年06月24日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to564377,788to377,2252016年01月21日2014年06月24日

Allele Location
Allele C7_01760C_B Ca22chr7B_C_albicans_SC5314:377788 to 377225 | JBrowse
Note: this feature is encoded on the Crick strand.
External Links CGOB | Entrez Gene (1, 2, 3) | Fungal Orthologs | FungiDB | GenBank (1, 2, 3, 4, 5, 6, 7, 8) | GenBank Patent Sequences | Non-periodic Expression | Pedant | PhylomeDB | TrEMBL
Primary CGDID CAL0000192594
ADDITIONAL INFORMATION for ISU1
Gene/Sequence Resources
REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ISU1]
1) Lan CY, et al. (2004) Regulatory networks affected by iron availability in Candida albicans. Mol Microbiol 53(5):1451-69
CGD Papers Entry Pubmed Entry Reference LINKOUT Web Supplement Data
2) CandidaDB
CGD Papers Entry
3) Berman J (2005) Mapping of ORFs in Assembly 4 to those in Assembly 19.
CGD Papers Entry
4) Chibana H, et al. (2005) Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome. Genetics 170(4):1525-37
CGD Papers Entry Pubmed Entry Reference LINKOUT
5) Maglott D, et al. (2007) Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res 35(Database issue):D26-31
CGD Papers Entry Pubmed Entry Reference LINKOUT Reference LINKOUT Reference LINKOUT Reference LINKOUT Reference LINKOUT
6) Nett JE, et al. (2009) Time course global gene expression analysis of an in vivo Candida biofilm. J Infect Dis 200(2):307-13
CGD Papers Entry Pubmed Entry Reference LINKOUT Web Supplement
7) Nobile CJ, et al. (2012) A recently evolved transcriptional network controls biofilm development in Candida albicans. Cell 148(1-2):126-38
CGD Papers Entry Pubmed Entry Reference LINKOUT Data

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