C. albicans OBPALPHA/C5_01775C Summary

Last curated 2014年09月18日
See the Literature Guide for most recent publications.

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Summary
Locus History Literature Gene Ontology Phenotype Homologs Protein
OBPALPHA BASIC INFORMATION [ View References ]
Standard Name OBPALPHA1
Systematic Name, Reference Strain C5_01775C_B (C. albicans SC5314)
Alias orf19.10709, orf19.10710, OBPalpha, C5_01775C, C5_01775C_A
Feature Type ORF, Verified
Description Similar to oxysterol binding protein; non-sex gene located within the MTLalpha mating-type-like locus (1, 2)
Literature
CUG Codons 1
Ortholog(s) in non-CGD species A. nidulans (AN3807) ; N. crassa (NCU03258)
Best hit(s) in non-CGD species S. pombe (SPCC23B6.01c) ; S. cerevisiae (OSH6)
Best hits in Candida species C. dubliniensis CD36 best hit(s) : Cd36_51550/OPBalpha
C. auris B8441 best hit(s) : B9J08_001454
C. parapsilosis CDC317 best hit(s) : CPAR2_303570
C. glabrata CBS138 best hit(s) : CAGL0K02849g
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JBrowse for feature C5_01775C_B

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GO Annotations View all OBPALPHA GO evidence and references

Molecular Function
Computational * lipid binding (IEA with EBI: Oxysterol-binding protein)

Biological Process
Manually curated * biological process involved in interspecies interaction between organisms (IMP)
* single-species biofilm formation on inanimate substrate (IMP)

Cellular Component
Manually curated * cellular_component unknown (ND)
Mutant Phenotype View all OBPALPHA Phenotype details and references
Classical genetics
heterozygous null * biofilm formation: decreased
* virulence: decreased

Sequence Information Ca22chr5B_C_albicans_SC5314:400901 to 399612 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年01月21日 | Sequence: 2014年09月18日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to1290400,901to399,6122016年01月21日2014年09月18日

Retrieve Sequences
Sequence Analysis Tools
Sequence Information Ca22chr5B_C_albicans_SC5314:400901 to 399612 | JBrowse
Note: this feature is encoded on the Crick strand.
External Links Fungal Orthologs | FungiDB | PhylomeDB | SwissProt | TrEMBL
Primary CGDID CAL0000202034
ADDITIONAL INFORMATION for OBPALPHA
Gene/Sequence Resources
LOCUS SUMMARY NOTES for OBPALPHA (Last Updated: 2014年09月19日)
REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for OBPALPHA]
1) Hull CM and Johnson AD (1999) Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans. Science 285(5431):1271-5
CGD Papers Entry Pubmed Entry Reference LINKOUT
2) Srikantha T, et al. (2012) Nonsex genes in the mating type locus of Candida albicans play roles in a/alpha biofilm formation, including impermeability and fluconazole resistance. PLoS Pathog 8(1):e1002476
CGD Papers Entry Pubmed Entry Reference LINKOUT Reference LINKOUT Reference LINKOUT Reference LINKOUT

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