C. albicans PGA31/C4_04080C Summary

Last curated 2022年04月12日
See the Literature Guide for most recent publications.

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Summary
Locus History Literature Gene Ontology Phenotype Homologs Protein
PGA31 BASIC INFORMATION [ View References ]
Standard Name PGA311
Systematic Name, Reference Strain C4_04080C_A (C. albicans SC5314)
Assembly 19/21 Identifier orf19.5302
Alias LDG52
orf19.12761, IPF21866.13 , IPF8535.23 , Contig4-2961_00184 , orf6.39325 , orf6.82905 , CA21563 , CaO19.53022 , IPF85353 , orf19.5302, C4_04080C_B, C4_04080C
Feature Type ORF, Verified
Description Cell wall protein; putative GPI anchor; expression regulated upon white-opaque switch; induced by Congo Red and cell wall regeneration; Bcr1-repressed in RPMI a/a biofilms (1, 6, 7, 8, 9, 10)
Literature
Name Description Predicted Gpi-Anchored1
Allele Name C4_04080C_B
Allelic Variation Non-synonymous variation between alleles
C4_04080C_B contains internal stop codons
Sequence variation between alleles within 100 bp upstream of feature start coordinates
Sequence variation between alleles within 100 bp downstream of feature end coordinates
CUG Codons C4_04080C_A: 0
C4_04080C_B: 0
Systematic Names Used in Other Strains CAWG_03397 (C. albicans WO-1)
Orthologous genes in Candida species C. auris B8441 Ortholog(s) : B9J08_000117/PGA26
C. dubliniensis CD36 Ortholog(s) : Cd36_43780
View ortholog cluster : 11 genes among 11 Candida-related species/strains
Best hits in Candida species C. parapsilosis CDC317 best hit(s) : CPAR2_402000/PGA30
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JBrowse for feature C4_04080C_A

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GO Annotations View all PGA31 GO evidence and references

Molecular Function
Manually curated * molecular_function unknown (ND)

Biological Process
Manually curated * cellular response to xenobiotic stimulus (IMP)
* fungal-type cell wall organization (IMP)

Cellular Component
Manually curated * cell surface (IDA)
* yeast-form cell wall (IDA)
High-throughput * cell surface (ISS)
Mutant Phenotype View all PGA31 Phenotype details and references
Classical genetics
homozygous null * cell wall morphology: abnormal
* chitin deposition: decreased
* resistance to Calcofluor White: decreased
* resistance to caspofungin: decreased
* viable

Large-scale survey
null * viable

Sequence Information Ca22chr4A_C_albicans_SC5314:875090 to 874032 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年01月21日 | Sequence: 2014年06月24日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to1059875,090to874,0322016年01月21日2014年06月24日

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Sequence Analysis Tools
Maps & Displays
Sequence Information Ca22chr4A_C_albicans_SC5314:875090 to 874032 | JBrowse
Note: this feature is encoded on the Crick strand.
Allele Location
Allele C4_04080C_B 		Ca22chr4B_C_albicans_SC5314:875114 to 874056 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年01月21日 | Sequence: 2014年06月24日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to1059875,114to874,0562016年01月21日2014年06月24日

Allele Location
Allele C4_04080C_B Ca22chr4B_C_albicans_SC5314:875114 to 874056 | JBrowse
Note: this feature is encoded on the Crick strand.
External Links CGOB | Entrez Gene (1, 2) | Fungal Orthologs | FungiDB | GenBank (1, 2, 3, 4, 5) | Non-periodic Expression | Pedant | PhylomeDB | TrEMBL
Primary CGDID CAL0000183944
ADDITIONAL INFORMATION for PGA31
Gene/Sequence Resources
REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PGA31]
1) De Groot PW, et al. (2003) Genome-wide identification of fungal GPI proteins. Yeast 20(9):781-96
CGD Papers Entry Pubmed Entry Reference LINKOUT Web Supplement Data
2) Maglott D, et al. (2007) Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res 35(Database issue):D26-31
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3) CandidaDB
CGD Papers Entry
4) Berman J (2005) Mapping of ORFs in Assembly 4 to those in Assembly 19.
CGD Papers Entry
5) CGD (2005) CGD comparison of orf6 and orf19 predicted protein products.
CGD Papers Entry
6) Lan CY, et al. (2002) Metabolic specialization associated with phenotypic switching in Candidaalbicans. Proc Natl Acad Sci U S A 99(23):14907-12
CGD Papers Entry Pubmed Entry Reference LINKOUT Web Supplement Data
7) Castillo L, et al. (2006) Genomic response programs of Candida albicans following protoplasting and regeneration. Fungal Genet Biol 43(2):124-34
CGD Papers Entry Pubmed Entry Reference LINKOUT Data
8) Castillo L, et al. (2008) A study of the Candida albicans cell wall proteome. Proteomics 8(18):3871-81
CGD Papers Entry Pubmed Entry Reference LINKOUT
9) Sorgo AG, et al. (2011) Effects of fluconazole on the secretome, the wall proteome, and wall integrity of the clinical fungus Candida albicans. Eukaryot Cell 10(8):1071-81
CGD Papers Entry Pubmed Entry Reference LINKOUT
10) Srikantha T, et al. (2013) Identification of genes upregulated by the transcription factor Bcr1 that are involved in impermeability, impenetrability, and drug resistance of Candida albicans a/alpha biofilms. Eukaryot Cell 12(6):875-88
CGD Papers Entry Pubmed Entry Reference LINKOUT

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