C. albicans GCN1/C2_10550C Summary

Last curated 2014年06月25日
See the Literature Guide for most recent publications.

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Summary
Locus History Literature Gene Ontology Phenotype Homologs Protein
GCN1 BASIC INFORMATION [ View References ]
Standard Name GCN11
Systematic Name, Reference Strain C2_10550C_A (C. albicans SC5314)
Assembly 19/21 Identifier orf19.5328
Alias orf19.12788, orf19.12789, orf19.12793, IPF21822.12 , IPF797.12 , Contig4-3102_00613 , orf6.83174 , orf6.83224 , orf6.83184 , CA54922 , CA54932 , orf19.5329, orf19.5333, GCN1.3f2 , orf19.5328, C2_10550C_B, C2_10550C
Feature Type ORF, Uncharacterized
Description Ortholog(s) have protein kinase activator activity, protein kinase regulator activity, stalled ribosome sensor activity (5)
Literature
Allele Name C2_10550C_B
Allelic Variation No allelic variation in feature
CUG Codons C2_10550C_A: 4
C2_10550C_B: 4
Systematic Names Used in Other Strains CAWG_06117 (C. albicans WO-1)
Orthologous genes in Candida species C. auris B8441 Ortholog(s) : B9J08_003589
C. parapsilosis CDC317 Ortholog(s) : CPAR2_407940
C. dubliniensis CD36 Ortholog(s) : Cd36_24780
C. glabrata CBS138 Ortholog(s) : CAGL0D01826g
View ortholog cluster : 19 genes among 19 Candida-related species/strains
Ortholog(s) in non-CGD species A. nidulans (AN10734) ; N. crassa (NCU05803) ; S. pombe (SPAC18G6.05c) ; S. cerevisiae (GCN1)
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JBrowse for feature C2_10550C_A

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GO Annotations View all GCN1 GO evidence and references

Molecular Function
Computational * protein kinase activator activity (IEA with S. pombe: SPAC18G6.05c)

Biological Process
Computational * mitotic G1 DNA damage checkpoint signaling (IEA with S. pombe: SPAC18G6.05c)
* negative regulation of cytoplasmic translational initiation (IEA with S. pombe: SPAC18G6.05c)
* positive regulation of autophagy (IEA with S. pombe: SPAC18G6.05c)

Cellular Component
Manually curated * cellular_component unknown (ND)
Mutant Phenotype View all GCN1 Phenotype details and references
Large-scale survey
heterozygous null * haploinsufficient

homozygous null * viable

null * viable

Sequence Information Ca22chr2A_C_albicans_SC5314:2179213 to 2171966 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年01月21日 | Sequence: 2014年06月24日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to72482,179,213to2,171,9662016年01月21日2014年06月24日

Retrieve Sequences
Sequence Analysis Tools
Maps & Displays
Sequence Information Ca22chr2A_C_albicans_SC5314:2179213 to 2171966 | JBrowse
Note: this feature is encoded on the Crick strand.
Allele Location
Allele C2_10550C_B 		Ca22chr2B_C_albicans_SC5314:2179080 to 2171833 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年01月21日 | Sequence: 2014年06月24日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to72482,179,080to2,171,8332016年01月21日2014年06月24日

Allele Location
Allele C2_10550C_B Ca22chr2B_C_albicans_SC5314:2179080 to 2171833 | JBrowse
Note: this feature is encoded on the Crick strand.
External Links BioGRID | CGOB | Entrez Gene (1, 2) | Fungal Orthologs | FungiDB | GenBank (1, 2, 3, 4, 5) | Non-periodic Expression | Pedant | PhylomeDB | TrEMBL
Primary CGDID CAL0000192579
ADDITIONAL INFORMATION for GCN1
Gene/Sequence Resources
REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GCN1]
1) Tzung KW, et al. (2001) Genomic evidence for a complete sexual cycle in Candida albicans. Proc Natl Acad Sci U S A 98(6):3249-53
CGD Papers Entry Pubmed Entry Reference LINKOUT Web Supplement
2) CandidaDB
CGD Papers Entry
3) Berman J (2005) Mapping of ORFs in Assembly 4 to those in Assembly 19.
CGD Papers Entry
4) CGD (2005) CGD comparison of orf6 and orf19 predicted protein products.
CGD Papers Entry
5) CGD (2010) Description lines for gene products, based on orthologs and predicted Gene Ontology (GO) annotations.
CGD Papers Entry

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