C. albicans QCR8/C2_04590C Summary

Last curated 2023年04月13日
See the Literature Guide for most recent publications.

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Summary
Locus History Literature Gene Ontology Phenotype Homologs Protein
QCR8 BASIC INFORMATION [ View References ]
Standard Name QCR81
Systematic Name, Reference Strain C2_04590C_A (C. albicans SC5314)
Assembly 19/21 Identifier orf19.4490.2
Alias IPF22763.12 , IPF4774.12 , Contig4-2993_00033 , CA14412 , orf19.4490.2, C2_04590C_B, C2_04590C
Feature Type ORF, Verified
Description Putative ubiquinol cytochrome c reductase; macrophage and pseudohyphal-induced protein; colony morphology-related gene regulation by Ssn6; Hap43-repressed; Spider biofilm repressed (1, 4, 5, 6, 7)
Literature
Allele Name C2_04590C_B
Allelic Variation No allelic variation in feature
Sequence variation between alleles within 100 bp downstream of feature end coordinates
CUG Codons C2_04590C_A: 0
C2_04590C_B: 0
Systematic Names Used in Other Strains CAWG_04215 (C. albicans WO-1)
Orthologous genes in Candida species C. parapsilosis CDC317 Ortholog(s) : CPAR2_103940
C. auris B8441 Ortholog(s) : B9J08_003126
C. dubliniensis CD36 Ortholog(s) : Cd36_19190
C. glabrata CBS138 Ortholog(s) : CAGL0I06270g
View ortholog cluster : 18 genes among 18 Candida-related species/strains
Ortholog(s) in non-CGD species A. nidulans (AN12213) ; N. crassa (qcr8) ; S. pombe (SPAC1782.07) ; S. cerevisiae (QCR8)
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JBrowse for feature C2_04590C_A

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GO Annotations View all QCR8 GO evidence and references

Molecular Function
Manually curated * molecular_function unknown (ND)

Biological Process
Manually curated * biological_process unknown (ND)

Cellular Component
High-throughput * plasma membrane (IDA)
Pathways * Aerobic Respiration (cyanide Sensitive) -- Electron Donors
Mutant Phenotype View all QCR8 Phenotype details and references
Classical genetics
homozygous null * vegetative growth: decreased rate
* viable

Large-scale survey
null * inviable

Sequence Information Ca22chr2A_C_albicans_SC5314:960128 to 959841 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年01月21日 | Sequence: 2014年06月24日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to288960,128to959,8412016年01月21日2014年06月24日

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Maps & Displays
Sequence Information Ca22chr2A_C_albicans_SC5314:960128 to 959841 | JBrowse
Note: this feature is encoded on the Crick strand.
Allele Location
Allele C2_04590C_B 		Ca22chr2B_C_albicans_SC5314:960158 to 959871 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年01月21日 | Sequence: 2014年06月24日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to288960,158to959,8712016年01月21日2014年06月24日

Allele Location
Allele C2_04590C_B Ca22chr2B_C_albicans_SC5314:960158 to 959871 | JBrowse
Note: this feature is encoded on the Crick strand.
External Links CGOB | Fungal Orthologs | FungiDB | GenBank (1, 2, 3, 4) | Non-periodic Expression | Pedant | PhylomeDB | TrEMBL | Transcription Modules
Primary CGDID CAL0000201360
ADDITIONAL INFORMATION for QCR8
Gene/Sequence Resources
REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for QCR8]
1) Garcia-Sanchez S, et al. (2005) Global roles of Ssn6 in Tup1- and Nrg1-dependent gene regulation in the fungal pathogen, Candida albicans. Mol Biol Cell 16(6):2913-25
CGD Papers Entry Pubmed Entry Reference LINKOUT Reference LINKOUT Web Supplement Web Supplement Data
2) CandidaDB
CGD Papers Entry
3) Berman J (2005) Mapping of ORFs in Assembly 4 to those in Assembly 19.
CGD Papers Entry
4) Singh V, et al. (2005) Global analysis of altered gene expression during morphogenesis of Candida albicans in vitro. Biochem Biophys Res Commun 334(4):1149-58
CGD Papers Entry Pubmed Entry Reference LINKOUT
5) Cabezon V, et al. (2009) Analysis of Candida albicans plasma membrane proteome. Proteomics 9(20):4770-86
CGD Papers Entry Pubmed Entry Reference LINKOUT
6) Singh RP, et al. (2011) Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans. J Biol Chem 286(28):25154-70
CGD Papers Entry Pubmed Entry Reference LINKOUT Data
7) Nobile CJ, et al. (2012) A recently evolved transcriptional network controls biofilm development in Candida albicans. Cell 148(1-2):126-38
CGD Papers Entry Pubmed Entry Reference LINKOUT Data

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